Pendoril Tablet 2 mg contains Perindopril Arginine, an angiotensin-converting enzyme (ACE) inhibitor used to treat hypertension (high blood pressure), heart failure, and to reduce cardiovascular risk. This lower-dose formulation is suitable for patients starting therapy, those requiring dose titration, or individuals who are sensitive to higher doses.

Perindopril works by inhibiting the conversion of angiotensin I to angiotensin II, a hormone responsible for narrowing blood vessels. This leads to relaxation of blood vessels, lowered blood pressure, and reduced workload on the heart, while protecting vital organs such as the heart and kidneys from damage caused by chronic hypertension.

Pendoril 2 mg can be used as monotherapy or in combination with other antihypertensive agents, providing flexibility for individualized treatment plans. It is especially helpful for patients with mild hypertension or those beginning long-term cardiovascular therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Features

• Contains Perindopril Arginine 2 mg per tablet

• ACE inhibitor for managing hypertension, heart failure, and cardiovascular risk

• Oral tablet for convenient once-daily administration

• Helps relax blood vessels and lower blood pressure

• Provides heart and kidney protection

• Suitable for initial therapy or dose titration

Indications

Pendoril Tablet 2 mg is indicated for:

• Hypertension: Effective in lowering high blood pressure and reducing cardiovascular complications

• Heart failure: Supports cardiac function and alleviates symptoms in patients with left ventricular dysfunction

• Cardiovascular risk reduction: Helps reduce the risk of myocardial infarction, stroke, and other cardiovascular events

• Mild hypertension: Appropriate starting dose for adults initiating ACE inhibitor therapy

Mechanism of Action

Perindopril Arginine acts as an ACE inhibitor by:

• Blocking the conversion of angiotensin I to angiotensin II, leading to vasodilation

• Reducing aldosterone secretion, decreasing sodium and water retention

• Lowering blood pressure and reducing the workload on the heart

• Protecting the cardiovascular system and kidneys from long-term hypertension-related damage

This dual effect ensures effective blood pressure control and organ protection.

Dosage and Administration

• Recommended starting dose: 2 mg orally once daily

• Can be taken with or without food, preferably at the same time each day

• Dose may be adjusted gradually based on blood pressure response and tolerance

• Blood pressure should be monitored regularly, especially during the initial stages of therapy

• Combination with other antihypertensive agents may be considered if needed

Possible Side Effects

Common side effects include:

• Dizziness or lightheadedness, especially after the first dose

• Fatigue or weakness

• Mild headache

• Dry cough

Rare but serious side effects may include:

• Angioedema (swelling of face, lips, or throat)

• Severe hypotension

• Kidney dysfunction

• Electrolyte imbalances

Patients should seek immediate medical attention if they experience severe swelling, difficulty breathing, or fainting.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Use under medical supervision, particularly in patients with kidney disease, low blood pressure, or heart failure

• Avoid use during pregnancy or breastfeeding

• Inform your healthcare provider about all other medications to prevent interactions

• Regular monitoring of blood pressure, kidney function, and electrolytes is recommended

Storage Instructions

• Store in a cool, dry place below 25°C

• Protect from light and moisture

• Keep tablets in the original container, tightly closed

• Keep out of reach of children.