Permin Cream 5% w/w contains Permethrin, a synthetic pyrethroid widely used as a topical scabicide and pediculicide. It is effective in the treatment of scabies and lice infestations by targeting the nervous system of parasites, causing paralysis and death. Permin Cream is formulated for topical application, providing localized, fast-acting relief from itching and infestation.

Permin Cream 5% w/w is recommended for adults and children over two months of age, offering a safe, convenient, and highly effective option for managing common parasitic skin infestations. Its formulation ensures uniform distribution and penetration, enhancing the elimination of mites and lice.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Highly effective in the treatment of scabies

• Treats head lice infestations

• Rapid relief from itching, irritation, and discomfort

• Topical application for localized treatment

• Safe for use in adults and children over 2 months

• Reduces risk of re-infestation when applied properly

Mechanism of Action

Permethrin, the active ingredient in Permin Cream, acts as a neurotoxin to parasites:

1. Disruption of Nerve Function:

   • Permethrin binds to sodium channels in the nerve cells of scabies mites and lice.

   • This prolongs sodium influx, leading to hyperexcitation of the nervous system, paralysis, and eventual death of the parasite.

2. Residual Activity:

   • Permethrin maintains activity on the skin for several hours, ensuring complete eradication of mites and lice.

3. Low Systemic Absorption:

   • Minimal absorption into the bloodstream makes Permin Cream safe for topical use, with limited systemic side effects.

Indications

Permin Cream 5% w/w is indicated for:

• Treatment of scabies caused by Sarcoptes scabiei

• Treatment of head lice infestations

• Relief from associated itching, inflammation, and irritation

Dosage and Administration

• Adults and Children: Apply a thin layer of Permin Cream 5% w/w over the affected areas.

• For scabies, apply from neck to toes, covering all skin folds, and leave on for 8–14 hours before washing off.

• For head lice, apply directly to the scalp and hair, leave for 10 minutes, then rinse thoroughly.

• Repeat treatment may be required after 7–10 days if live lice or mites persist.

• Wash hands thoroughly after application.

• Avoid contact with eyes, mouth, and mucous membranes.

Precautions and Warnings

• For external use only; do not ingest.

• Avoid using on broken, irritated, or infected skin unless advised by a healthcare professional.

• Use caution in infants under 2 months, pregnant, or breastfeeding women; consult a physician before use.

• Seek medical advice if symptoms persist or worsen after treatment.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Permin Cream is generally well-tolerated. Side effects may include:

• Mild burning, stinging, or redness at the application site

• Temporary itching or irritation

• Rare allergic reactions, including rash or swelling

If severe irritation occurs, discontinue use and consult a physician.

Storage

Store below 30°C in a cool, dry place, protected from light. Keep out of reach of children.

Permin Cream 5% w/w provides effective, fast-acting treatment for scabies and lice infestations, relieving itching and discomfort while ensuring safe topical application.