Plasmex Injection 6%+0.9% is a sterile intravenous solution containing Hydroxyethyl Starch (HES) and Sodium Chloride. It is primarily used as a plasma volume expander in the management of hypovolemia (low blood volume) caused by acute blood loss, trauma, surgery, or severe dehydration. This formulation helps restore and maintain circulatory volume, ensuring adequate tissue perfusion and oxygen delivery.
রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন
Composition
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Hydroxyethyl Starch (HES) 6%
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Sodium Chloride 0.9%
Mechanism of Action
Hydroxyethyl Starch is a colloid solution that increases plasma volume by retaining fluid within the blood vessels. It works by:
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Expanding intravascular volume
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Improving blood circulation and cardiac output
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Maintaining hemodynamic stability
Sodium Chloride 0.9% (normal saline) helps maintain electrolyte balance and contributes to fluid replacement.
Indications
Plasmex Injection is indicated for:
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Treatment of hypovolemia due to acute blood loss
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Fluid resuscitation in surgical or trauma patients
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Maintenance of blood volume during major operations
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Shock management when crystalloids alone are insufficient
Dosage and Administration
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Administered intravenously under strict medical supervision
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Dosage depends on patient condition, body weight, and severity of fluid loss
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Infusion rate should be carefully monitored to avoid fluid overload
Benefits
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Rapid restoration of circulating blood volume
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Improves tissue perfusion and oxygen delivery
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Provides effective support in emergency and critical care settings
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Helps stabilize blood pressure in hypovolemic conditions
Side Effects
Possible side effects may include:
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Allergic or anaphylactic reactions
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Itching (pruritus)
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Coagulation disturbances with prolonged use
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Fluid overload or edema
Immediate medical attention is required if severe reactions occur.
রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন
Precautions
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Contraindicated in patients with severe kidney impairment or renal failure
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Use cautiously in patients with heart failure or coagulation disorders
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Monitor kidney function and fluid balance during therapy
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Not recommended for critically ill patients without careful evaluation
Storage
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Store at controlled room temperature
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Protect from light
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Do not freeze
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Keep out of reach of children.