Pofol Emulsion for Infusion contains Propofol, a short-acting intravenous anesthetic agent used for the induction and maintenance of general anesthesia, as well as sedation in intensive care settings and during diagnostic or surgical procedures. It provides rapid onset and smooth recovery, making it widely used in hospital anesthesia practice.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Propofol 200 mg per 20 ml emulsion

Indications

Pofol Emulsion is indicated for:

• Induction of general anesthesia
• Maintenance of general anesthesia (as part of balanced anesthesia)
• Sedation in intensive care unit (ICU) patients on mechanical ventilation
• Procedural sedation for diagnostic or minor surgical procedures
• Sedation during endoscopy or imaging procedures

Mechanism of Action

Propofol enhances the activity of gamma-aminobutyric acid (GABA), the primary inhibitory neurotransmitter in the central nervous system. This results in sedation, hypnosis, and loss of consciousness. Its rapid redistribution and metabolism contribute to its quick onset and short duration of action.

Dosage and Administration

• Administered intravenously by trained healthcare professionals only.
• Dosage is individualized based on patient age, weight, and clinical condition.
• Continuous monitoring of cardiovascular and respiratory function is essential during use.
• Should be used only in settings equipped for airway management and resuscitation.

Benefits

• Rapid onset of anesthesia and sedation
• Smooth and controlled induction and recovery
• Useful in ICU and surgical settings
• Short duration of action allows quick patient recovery
• Effective for procedural sedation

Side Effects

Pofol Emulsion may cause:

• Hypotension
• Respiratory depression or apnea
• Bradycardia
• Pain at injection site
• Dizziness or drowsiness during recovery
• Rare allergic reactions

Serious adverse effects require immediate medical attention and monitoring.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• For intravenous use only under strict medical supervision.
• Must be administered by trained anesthesia personnel.
• Continuous monitoring of vital signs is mandatory.
• Use with caution in patients with cardiovascular, respiratory, or hepatic impairment.
• Aseptic technique must be followed to prevent contamination (emulsion supports microbial growth).

Storage

• Store below 25°C
• Do not freeze
• Protect from light
• Use immediately after opening as per hospital protocol
• Discard unused portion.