Pregan ER Tablet 165 mg contains Pregabalin in an extended-release (ER) formulation. It is used for the treatment of neuropathic pain and other nerve-related conditions. The extended-release technology allows the medicine to be released slowly over time, providing long-lasting pain relief and stable therapeutic effects throughout the day.

Pregabalin helps reduce abnormal nerve activity, thereby decreasing pain sensations and improving daily functioning in patients with chronic nerve disorders.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Pregan ER Tablet 165 mg is indicated for:

• Neuropathic pain (diabetic neuropathy, post-herpetic neuralgia)
• Peripheral nerve pain
• Chronic neuropathic pain conditions
• Fibromyalgia (as prescribed)
• Adjunct therapy in partial seizures (epilepsy)
• Generalized anxiety disorder (in selected cases under medical supervision)

Mechanism of Action

Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. This reduces the release of excitatory neurotransmitters such as glutamate, norepinephrine, and substance P. By stabilizing nerve activity, it helps relieve pain, reduce seizure frequency, and calm overactive nerve signals.

The ER formulation ensures gradual absorption and sustained effect over an extended period.

Dosage and Administration

• Take only as prescribed by a physician
• Usually taken once daily due to extended-release formulation
• Swallow the tablet whole with water; do not crush or chew
• Can be taken with or without food
• Do not stop suddenly; taper dose gradually under medical supervision

Benefits

• Provides long-lasting relief from nerve pain
• Maintains steady drug levels throughout the day
• Reduces need for multiple daily dosing
• Improves sleep disturbed by chronic pain
• Helps manage fibromyalgia and anxiety symptoms

Side Effects

Common side effects may include:

• Dizziness
• Drowsiness
• Dry mouth
• Blurred vision
• Weight gain
• Peripheral edema (swelling of hands or feet)

Serious side effects may include:

• Mood changes or depression
• Allergic reactions
• Suicidal thoughts (rare but important to monitor)

Seek medical attention if severe symptoms occur.

Precautions and Warnings

• May cause dizziness and drowsiness; avoid driving if affected
• Use cautiously in patients with kidney impairment
• Avoid alcohol as it may increase sedation
• Do not discontinue abruptly
• Monitor for mood or behavioral changes
• Use during pregnancy or breastfeeding only if prescribed

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Pregan ER Tablet may interact with:

• CNS depressants (sedatives, alcohol)
• Opioid pain medications
• Anti-anxiety drugs

Always inform your healthcare provider about all medications being used.

Storage

• Store below 30°C in a cool and dry place
• Protect from light and moisture
• Keep out of reach of children.