Platinex Injection 1 mg/ml contains Cisplatin, a platinum-based chemotherapy agent widely used in the treatment of various types of cancers. It works by interfering with the growth and spread of cancer cells in the body. Platinex is commonly administered in hospital settings under the supervision of experienced oncologists as part of combination chemotherapy regimens.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Cisplatin 1 mg/ml

Mechanism of Action

Cisplatin exerts its anticancer effects by binding to DNA and forming cross-links within and between DNA strands. This action:

• Inhibits DNA replication and transcription
• Prevents cancer cell division
• Leads to programmed cell death (apoptosis)

Its cytotoxic effect is particularly effective against rapidly dividing cancer cells.

Indications

Platinex Injection is indicated for the treatment of:

• Testicular cancer
• Ovarian cancer
• Bladder cancer
• Lung cancer (including non-small cell and small cell lung cancer)
• Head and neck cancers
• Other solid tumors as part of combination therapy

Dosage and Administration

• Administered intravenously under strict medical supervision
• Dosage depends on body surface area, type of cancer, and patient condition
• Adequate hydration is essential before and after administration to reduce toxicity
• Often used in combination with other chemotherapy agents

Benefits

• Highly effective against a wide range of solid tumors
• Proven role in combination chemotherapy regimens
• Helps control tumor growth and spread
• Improves survival outcomes in several cancers

Side Effects

Cisplatin therapy may cause significant side effects, including:

• Nausea and vomiting
• Kidney toxicity (nephrotoxicity)
• Hearing loss (ototoxicity)
• Bone marrow suppression (leading to anemia, leukopenia, thrombocytopenia)
• Electrolyte imbalance (low magnesium, potassium)

Close monitoring is required during treatment.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Contraindicated in patients with severe renal impairment
• Regular monitoring of kidney function, blood counts, and electrolytes is essential
• Use with caution in patients with hearing disorders
• Not recommended during pregnancy or breastfeeding
• Adequate hydration must be ensured to minimize toxicity

Storage

• Store at controlled room temperature
• Protect from light
• Do not freeze
• Keep out of reach of children.