Foly Tablet 15 mg contains Folinic Acid, also known as Leucovorin, a biologically active form of folate (Vitamin B9). Unlike folic acid, folinic acid does not require conversion by the enzyme dihydrofolate reductase to become active, making it immediately available for use in the body. Folinic acid plays a crucial role in DNA synthesis, repair, and cellular growth, particularly in rapidly dividing cells.

Foly Tablet is commonly used in combination with certain chemotherapeutic agents, such as Methotrexate and 5-Fluorouracil, to reduce drug-related toxicities while preserving therapeutic efficacy. It also helps in the treatment of folate deficiency, megaloblastic anemia, and conditions where folate metabolism is impaired.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Foly Tablet 15 mg is indicated for:

• Folate deficiency due to poor dietary intake, malabsorption, or chronic illnesses

• Megaloblastic anemia caused by folate deficiency

• Chemotherapy support: as a “rescue” therapy to reduce Methotrexate toxicity

• Enhancing the efficacy of 5-Fluorouracil in cancer therapy

• Prevention of congenital folate deficiency-related disorders during pregnancy (as advised)

• Treatment of specific metabolic disorders involving impaired folate metabolism

Foly is suitable for adults and children, but dosage should be guided by a healthcare professional based on the condition being treated.

Dosage and Administration

The dosage of Foly Tablet depends on the condition being treated:

• Folate deficiency and megaloblastic anemia: 5–15 mg daily orally, or as prescribed

• Methotrexate rescue therapy: Dosage and timing depend on Methotrexate regimen; usually given shortly after chemotherapy administration

• Enhancement of 5-Fluorouracil therapy: Administered in combination according to oncologist instructions

Administration instructions:

• Take the tablet orally with a glass of water

• Can be taken with or without food

• Follow the prescribed schedule carefully, especially when used with chemotherapy

• Do not exceed the recommended dose without medical advice

Benefits

• Provides immediate folate activity without requiring metabolic conversion

• Prevents and treats folate deficiency and related anemia

• Reduces toxic side effects of Methotrexate in chemotherapy

• Enhances the effectiveness of certain chemotherapeutic regimens

• Supports DNA synthesis and healthy cell division, critical in growth, pregnancy, and repair

Side Effects

Foly Tablet 15 mg is generally well tolerated. Mild side effects may include:

• Nausea or mild gastrointestinal discomfort

• Loss of appetite

• Sleep disturbances or fatigue

• Allergic reactions such as rash or itching (rare)

Serious side effects are uncommon but may occur if taken in excessive doses or in combination with certain medications. Patients should report unusual symptoms to their physician promptly.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Use under medical supervision, especially in patients with renal or liver impairment

• Inform your doctor of all medications and supplements being taken to avoid interactions

• Not recommended as a substitute for dietary folate without medical advice

• Pregnant and breastfeeding women should use only as directed

• Monitor blood counts during long-term therapy, particularly when used with chemotherapy

Storage

Store below 30°C in a dry, light-protected place. Keep the tablets out of reach of children and ensure the container is tightly closed.

Foly Tablet 15 mg (Folinic Acid) is a safe and effective supplement for treating folate deficiency, supporting chemotherapy regimens, and promoting healthy DNA synthesis and cell function under proper medical supervision.