Prelin Capsule 50 mg contains Pregabalin, an anticonvulsant and neuropathic pain-modulating agent widely used for the management of neuropathic pain, epilepsy, and generalized anxiety disorder (GAD). Pregabalin works by stabilizing overactive nerve signals in the central nervous system, reducing excessive neuronal excitability, and alleviating pain caused by nerve damage.

Prelin Capsule 50 mg is designed for oral administration and provides effective symptomatic relief for patients suffering from conditions such as diabetic neuropathy, postherpetic neuralgia, fibromyalgia, and seizure disorders. Its ability to modulate nerve signaling makes it a versatile option for both chronic pain management and adjunctive seizure control.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Mechanism of Action

Pregabalin binds to the α2-δ subunit of voltage-gated calcium channels in the central nervous system. This binding:

• Reduces calcium influx into nerve terminals

• Decreases the release of excitatory neurotransmitters such as glutamate, norepinephrine, and substance P

• Dampens overactive nerve signaling, which reduces neuropathic pain, seizures, and anxiety symptoms

By targeting the abnormal nerve activity directly, Pregabalin provides effective symptom relief without significant sedation in most patients.

Indications

Prelin Capsule 50 mg is indicated for:

• Neuropathic pain associated with conditions such as:

  • Diabetic peripheral neuropathy

  • Postherpetic neuralgia

  • Spinal cord injury-related neuropathy

• Adjunct therapy for partial-onset seizures in adults with epilepsy

• Generalized anxiety disorder (GAD) in adults

• Fibromyalgia and other chronic pain syndromes as prescribed by a physician

It is suitable for patients requiring mild to moderate pain relief or initial therapy for neuropathic conditions.

Dosage and Administration

• The usual starting dose is 50 mg orally, 2–3 times daily, depending on the patient’s condition and response

• Capsules should be taken with or without food and swallowed whole with water

• Dose may be gradually increased based on efficacy and tolerance, with maximum daily doses determined by the prescribing physician

• Regular monitoring of symptom relief, side effects, and renal function is recommended

• Abrupt discontinuation should be avoided; gradual tapering is advised to prevent withdrawal symptoms

Benefits of Prelin Capsule 50 mg

• Provides effective relief from neuropathic pain

• Reduces frequency and severity of seizures as adjunct therapy

• Alleviates anxiety symptoms in generalized anxiety disorder

• Helps improve quality of life and daily functioning in patients with chronic pain or nerve disorders

• Generally well tolerated with a predictable safety profile

Possible Side Effects

Common side effects may include:

• Dizziness or drowsiness

• Mild weight gain

• Blurred vision

• Dry mouth or constipation

Serious side effects are rare but can include:

• Allergic reactions such as rash or swelling

• Severe dizziness or confusion

• Muscle pain or weakness

Patients should report persistent or severe side effects to their healthcare provider immediately.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Use cautiously in patients with renal impairment, as dose adjustment may be required

• Avoid alcohol and other sedatives unless approved by a physician

• Not recommended during pregnancy or breastfeeding without medical supervision

• Avoid abrupt discontinuation to prevent withdrawal symptoms such as insomnia, headache, or nausea

• Inform the doctor of all other medications to avoid drug interactions

Storage

Store below 30°C in a dry, dark place. Keep the container tightly closed and out of reach of children. Do not use after the expiration date.

Prelin Capsule 50 mg offers effective management of neuropathic pain, seizures, and anxiety symptoms, improving patient comfort and quality of life when used under proper medical supervision.