Profen Tablet 400 mg contains Ibuprofen, a widely used nonsteroidal anti-inflammatory drug (NSAID) known for its analgesic, anti-inflammatory, and antipyretic properties. It is commonly prescribed for the relief of pain, inflammation, and fever associated with a variety of conditions, ranging from musculoskeletal injuries to chronic inflammatory disorders. Profen provides effective symptomatic relief and improves comfort, mobility, and daily functioning.

Ibuprofen works by inhibiting the cyclooxygenase (COX) enzymes COX-1 and COX-2. These enzymes play a key role in the production of prostaglandins, chemical mediators responsible for pain, inflammation, and fever. By reducing prostaglandin synthesis, Profen Tablet alleviates pain, decreases inflammation, and lowers body temperature in febrile conditions.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Ibuprofen 400 mg (oral)

Indications

Profen Tablet 400 mg is indicated for the management of:

• Mild to moderate pain, including headaches, dental pain, menstrual pain, and musculoskeletal pain

• Inflammatory conditions such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis

• Fever reduction in acute febrile conditions

• Post-operative pain relief and inflammation control

• Soft tissue injuries such as sprains, strains, and sports-related injuries

Mechanism of Action

Ibuprofen, the active ingredient in Profen Tablet, acts by:

• Blocking COX-1 and COX-2 enzymes, thereby reducing prostaglandin synthesis

• Decreasing the inflammatory response in tissues

• Relieving pain and swelling

• Lowering fever by acting on the hypothalamus to regulate body temperature

This dual action provides rapid and effective relief from pain, inflammation, and fever while supporting recovery from acute or chronic conditions.

Dosage and Administration

The dosage of Profen Tablet 400 mg should be determined by a healthcare professional based on the severity of symptoms, age, and patient health condition.

• Typically taken orally with water, preferably after meals to minimize gastrointestinal irritation.

• The usual adult dose is 400 mg every 6–8 hours as needed, not exceeding 1,200 mg per day without medical advice.

• For chronic inflammatory conditions, dosing may be adjusted under medical supervision.

• Swallow tablets whole; do not crush or chew unless prescribed.

Precautions and Warnings

• Use with caution in patients with a history of gastrointestinal ulcers, bleeding disorders, kidney or liver impairment, and cardiovascular diseases.

• Long-term or high-dose use may increase the risk of gastrointestinal bleeding or cardiovascular events.

• Avoid concurrent use with other NSAIDs unless prescribed by a healthcare professional.

• Inform your doctor about any other medications, including anticoagulants, antihypertensives, and corticosteroids.

• Consult a physician before use during pregnancy or breastfeeding.

Possible Side Effects

Profen Tablet 400 mg is generally well tolerated, but some patients may experience:

• Gastrointestinal discomfort, nausea, or heartburn

• Stomach ulcers or bleeding (rare, especially with prolonged use)

• Dizziness or headache

• Rash or mild allergic reactions

• Fluid retention or mild swelling in sensitive individuals

Seek immediate medical attention if severe allergic reactions, gastrointestinal bleeding, or unusual symptoms occur.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage Instructions

• Store below 30°C in a cool, dry place.

• Protect from light and moisture.

• Keep out of reach of children.

Conclusion

Profen Tablet 400 mg (Ibuprofen) is a versatile NSAID that effectively relieves pain, reduces inflammation, and lowers fever. With proper medical supervision, it provides rapid and reliable relief from acute or chronic conditions, enhancing patient comfort and supporting recovery.