Prolimus Ointment 0.10% contains tacrolimus monohydrate, a topical immunomodulator used in the management of moderate to severe atopic dermatitis (eczema). It helps reduce inflammation, itching, and redness by modulating the skin’s immune response. This higher-strength formulation is generally used in adults or more resistant cases under medical supervision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Tacrolimus Monohydrate 0.10% w/w
• Dosage Form: Topical ointment

Mechanism of Action

Tacrolimus works by inhibiting calcineurin, an enzyme involved in activating T-lymphocytes. This reduces the release of inflammatory cytokines responsible for skin inflammation, itching, and redness. Unlike corticosteroids, it does not cause skin thinning, making it suitable for long-term management in selected patients.

Indications

Prolimus Ointment 0.10% is indicated for:

• Moderate to severe atopic dermatitis (eczema) in adults
• Chronic or steroid-resistant eczema
• Facial and flexural eczema (sensitive skin areas)
• Maintenance therapy to prevent flare-ups
• Inflammatory skin conditions as prescribed by a physician

Dosage and Administration

• Apply a thin layer to the affected area
• Use 1–2 times daily or as directed by a physician
• Apply on clean, dry skin only
• Avoid occlusive dressings unless advised
• Wash hands after application unless treating hands

Benefits

• Reduces itching, redness, and inflammation
• Effective in moderate to severe eczema
• Suitable for sensitive skin areas
• Steroid-free alternative therapy
• Helps reduce frequency of flare-ups

Possible Side Effects

Common side effects may include:

• Burning or stinging sensation at application site
• Skin redness or irritation
• Itching

Less common side effects may include:

• Increased sensitivity to sunlight
• Skin infections (rare)
• Mild flu-like symptoms (rare)

Precautions and Warnings

• For external use only
• Avoid application on infected or broken skin unless advised
• Minimize exposure to sunlight and use sun protection
• Not recommended for prolonged unsupervised use
• Use only under medical supervision, especially in children and sensitive patients

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

• Store below 30°C in a cool, dry place
• Do not freeze
• Protect from light
• Keep out of reach of children

Conclusion

Prolimus Ointment 0.10% (Tacrolimus Monohydrate) is a potent steroid-free topical treatment for moderate to severe eczema. It effectively controls inflammation and itching while being suitable for long-term use under proper medical guidance.