Protace-H Tablet 2.5 mg+12.5 mg combines Ramipril (2.5 mg) and Hydrochlorothiazide (12.5 mg), providing a synergistic therapy for the effective management of hypertension (high blood pressure). Ramipril is an angiotensin-converting enzyme (ACE) inhibitor that relaxes blood vessels and reduces blood pressure, while Hydrochlorothiazide is a thiazide diuretic that promotes the excretion of excess salt and water from the body. Together, they offer a dual mechanism to control blood pressure and reduce cardiovascular risk.

Protace-H is particularly beneficial for patients whose blood pressure is not adequately controlled with a single medication. The combination ensures more stable blood pressure management, reduces strain on the heart, and lowers the risk of complications such as heart attack, stroke, and kidney damage. Its oral tablet formulation provides convenient once-daily dosing for better patient compliance.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Features

• Active Ingredients: Ramipril 2.5 mg (ACE inhibitor) + Hydrochlorothiazide 12.5 mg (diuretic)

• Dual Mechanism of Action: Relaxes blood vessels and reduces fluid retention for effective blood pressure control.

• Supports Heart Health: Reduces strain on the heart and lowers the risk of cardiovascular events.

• Renal Protection: Helps prevent kidney damage associated with hypertension.

• Convenient Oral Tablet: Once-daily dosing for ease of use and better compliance.

Indications

Protace-H Tablet 2.5 mg+12.5 mg is indicated for:

• Management of essential hypertension

• Patients requiring combination therapy due to inadequate blood pressure control with monotherapy

• Reduction of cardiovascular risk in patients with high blood pressure

• Prevention of kidney complications in hypertensive patients

Mechanism of Action

The combination of Ramipril and Hydrochlorothiazide works through complementary mechanisms:

1. Ramipril (ACE Inhibitor): Blocks the conversion of angiotensin I to angiotensin II, reducing vasoconstriction and lowering blood pressure.

2. Hydrochlorothiazide (Diuretic): Promotes excretion of sodium and water through the kidneys, decreasing blood volume and reducing blood pressure.

3. Enhanced Cardiovascular Protection: Together, they reduce cardiac workload and improve blood flow.

4. Renal Benefits: Lowering blood pressure and reducing fluid retention helps protect kidney function.

This dual-action approach ensures effective and sustained blood pressure management while supporting overall cardiovascular and renal health.

Dosage and Administration

• Adults: 1 tablet orally once daily, preferably in the morning, or as directed by a physician.

• The tablet should be swallowed whole with water; can be taken with or without food.

• Dose adjustments may be required based on blood pressure response, kidney function, and electrolyte levels.

• Regular monitoring of blood pressure, kidney function, and serum electrolytes is recommended.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Safety and Precautions

• May cause dizziness, fatigue, headache, or mild cough; patients should rise slowly from sitting or lying positions.

• Use with caution in patients with impaired kidney or liver function.

• Avoid use during pregnancy and breastfeeding unless prescribed by a physician.

• Inform your doctor about all medications to avoid interactions, especially with potassium supplements, other diuretics, or NSAIDs.

• Store in a cool, dry place below 25°C, protected from light and moisture, and keep out of reach of children.

Protace-H Tablet 2.5 mg+12.5 mg provides effective combination therapy for hypertension, offering improved blood pressure control, cardiovascular protection, and kidney support in a convenient oral formulation.