Ramicard Plus Tablet 5 mg + 25 mg is a fixed-dose combination antihypertensive medicine containing Ramipril, an angiotensin-converting enzyme (ACE) inhibitor, and Hydrochlorothiazide, a thiazide diuretic. This higher-strength formulation is designed for patients who require stronger blood pressure control when monotherapy or lower-dose combination therapy is insufficient.

By combining two complementary mechanisms of action, Ramicard Plus effectively lowers blood pressure, reduces cardiovascular strain, and minimizes the risk of serious complications such as heart attack, stroke, heart failure, and kidney damage.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Ramipril 5 mg

• Hydrochlorothiazide 25 mg

Mechanism of Action

Ramipril works by blocking the angiotensin-converting enzyme, thereby reducing the formation of angiotensin II. This leads to relaxation and widening of blood vessels, improved blood flow, and reduced workload on the heart. It also decreases aldosterone secretion, limiting sodium and water retention.

Hydrochlorothiazide acts on the kidneys to increase the excretion of sodium and water through urine. This reduces blood volume and helps lower blood pressure. The diuretic effect also supports long-term cardiovascular protection.

Together, these two agents provide enhanced antihypertensive efficacy compared to single-agent therapy.

Indications

Ramicard Plus Tablet 5 mg + 25 mg is indicated for:

• Treatment of hypertension in patients requiring combination therapy

• Patients inadequately controlled with single-drug treatment

• Long-term management of high cardiovascular risk associated with elevated blood pressure

Dosage and Administration

The dosage should be determined by a physician according to the patient’s condition and treatment response. It is generally taken once daily, preferably in the morning to minimize nighttime urination due to the diuretic component. The tablet may be taken with or without food, but should be taken consistently at the same time each day.

Patients are advised not to stop the medication suddenly without medical consultation.

Benefits

• Provides potent and sustained blood pressure reduction

• Combines two effective antihypertensive agents in one tablet

• Reduces risk of heart attack, stroke, and heart failure

• Helps manage fluid retention

• Convenient once-daily dosing for improved compliance

Precautions

Caution is advised in patients with renal or hepatic impairment, electrolyte imbalance, dehydration, diabetes, or gout. Regular monitoring of blood pressure, kidney function, and serum electrolytes—especially potassium and sodium—is recommended during therapy.

This medication is contraindicated during pregnancy due to the risk of fetal harm. Patients with a history of angioedema or hypersensitivity to ACE inhibitors or sulfonamide-derived drugs should inform their healthcare provider before use.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects may include:

• Dizziness or lightheadedness

• Persistent dry cough

• Increased urination

• Fatigue

• Electrolyte disturbances

Serious reactions such as severe dehydration, swelling of the face or throat, or allergic reactions require immediate medical attention.

Storage

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.

Ramicard Plus Tablet 5 mg + 25 mg offers effective, high-strength combination therapy for patients requiring advanced blood pressure control under professional medical supervision.