Symbion Inhaler (160 mcg + 4.5 mcg)/puff is a combination inhalation therapy containing Budesonide and Formoterol Fumarate. It is formulated to provide effective long-term control of asthma and chronic obstructive pulmonary disease (COPD). This inhaler delivers a fixed dose of medication with each actuation, ensuring accurate and consistent dosing.

Symbion Inhaler combines the anti-inflammatory action of an inhaled corticosteroid with the long-acting bronchodilatory effect of a beta2-agonist. This dual mechanism helps reduce airway inflammation, prevent bronchospasm, and improve lung function. Regular use supports better symptom control, reduces exacerbations, and enhances quality of life for patients with chronic respiratory conditions.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Class

Combination Inhaled Corticosteroid (ICS) and Long-Acting Beta2-Agonist (LABA)

Indications

Symbion Inhaler (160 mcg + 4.5 mcg)/puff is indicated for:

• Maintenance treatment of asthma in adults and adolescents

• Prevention of asthma symptoms including wheezing, breathlessness, and chest tightness

• Maintenance treatment of moderate to severe COPD

• Reduction in the frequency of asthma and COPD exacerbations

It is intended for regular maintenance therapy and is not suitable for the immediate relief of acute bronchospasm.

Pharmacology

Budesonide is a potent inhaled corticosteroid that reduces inflammation in the respiratory tract. It suppresses inflammatory cell activity and decreases airway swelling and mucus production, improving airway responsiveness over time.

Formoterol Fumarate is a long-acting selective beta2-adrenergic receptor agonist that relaxes bronchial smooth muscle. It produces rapid and sustained bronchodilation, helping to keep airways open for up to 12 hours.

The combination of Budesonide and Formoterol addresses both the inflammatory and bronchoconstrictive components of asthma and COPD, providing comprehensive and sustained respiratory control.

Dosage and Administration

The dosage should be determined by a registered healthcare professional based on disease severity.

• Typically administered as one or two inhalations twice daily

• Shake the inhaler well before use

• Inhale deeply and hold breath for a few seconds after each puff

• Rinse the mouth with water after use to reduce the risk of oral fungal infection

Patients should use the inhaler regularly, even if symptoms improve, to maintain optimal control.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Not for relief of acute asthma attacks; a short-acting bronchodilator should be available for emergency use

• Use with caution in patients with cardiovascular disease, diabetes, hypertension, or hyperthyroidism

• Long-term use of corticosteroids may cause systemic effects at high doses

• Monitor patients regularly for symptom control and inhaler technique

Possible Side Effects

Common side effects may include:

• Throat irritation

• Hoarseness

• Oral candidiasis

• Headache

• Tremor

• Palpitations

Most side effects are mild and can be minimized with proper inhaler technique and mouth rinsing after use.

Storage

Store below 30°C in a cool, dry place away from direct sunlight. Keep out of reach of children. Do not puncture or expose the inhaler to excessive heat.