Regora Tablet 40 mg contains Regorafenib Monohydrate, an oral multi-kinase inhibitor used in the treatment of certain advanced cancers. It works by blocking multiple enzymes involved in tumor growth, angiogenesis (blood vessel formation), and cancer cell proliferation. Regora is typically used in patients with metastatic or refractory cancers under strict oncologist supervision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Regorafenib Monohydrate 40 mg

Mechanism of Action

Regorafenib is a multi-targeted tyrosine kinase inhibitor that acts on several pathways involved in cancer progression. Its actions include:

• Inhibition of tumor angiogenesis (blocking VEGFR and TIE2 pathways)
• Suppression of tumor cell proliferation (via RAF kinase inhibition)
• Interference with tumor microenvironment signaling
• Reduction of cancer growth and metastasis

Indications

Regora Tablet is indicated for:

• Metastatic colorectal cancer (mCRC) in previously treated patients
• Gastrointestinal stromal tumors (GIST) resistant to prior therapy
• Advanced hepatocellular carcinoma (HCC) after sorafenib therapy

Dosage and Administration

• To be taken strictly under the supervision of an oncologist
• Usually administered once daily for 21 days followed by a 7-day break (28-day cycle)
• Should be taken with a low-fat meal
• Swallow whole with water; do not crush or chew
• Dose may be adjusted based on tolerance and side effects

Benefits

• Slows tumor growth and progression
• Blocks multiple cancer-promoting pathways
• Improves disease control in advanced cancers
• Oral administration allows convenient use
• Effective in patients resistant to prior treatments

Side Effects

Common side effects may include:

• Fatigue and weakness
• Hand-foot skin reaction (redness, pain, blistering)
• Diarrhea
• Loss of appetite
• Hypertension (high blood pressure)
• Liver function abnormalities

Serious side effects require immediate medical attention.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Regular monitoring of liver function and blood pressure is required
• Not recommended during pregnancy or breastfeeding
• Use cautiously in patients with liver impairment
• Inform your doctor about all medications being taken
• Dose interruption or modification may be required for toxicity

Storage

• Store below 30°C in a dry place
• Protect from light and moisture
• Keep out of reach of children.