Renesis Tablet 150 mg contains Roxadustat, an oral hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor used for the treatment of anemia associated with chronic kidney disease (CKD). It helps stimulate the body’s natural erythropoietin production, supporting red blood cell formation and increasing hemoglobin levels. This highest-strength formulation is used in selected patients requiring intensive anemia management under strict specialist supervision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Roxadustat 150 mg

Mechanism of Action

Roxadustat works by stabilizing hypoxia-inducible factor (HIF), resulting in:

• Increased endogenous erythropoietin production in the kidneys
• Enhanced iron absorption and mobilization
• Improved red blood cell production in the bone marrow
• Correction of anemia associated with chronic kidney disease

This helps restore oxygen-carrying capacity in the blood through a physiological pathway.

Indications

Renesis Tablet 150 mg is indicated for:

• Anemia associated with chronic kidney disease (CKD) in adults
• Patients on dialysis or non-dialysis CKD therapy (as prescribed by a nephrologist)

Dosage and Administration

• To be taken strictly under the supervision of a nephrologist
• Usually administered orally three times weekly or as directed by a physician
• Can be taken with or without food
• Dose is individualized based on hemoglobin response and iron status
• Regular laboratory monitoring is essential during therapy

Benefits

• Effectively increases hemoglobin levels
• Reduces fatigue, weakness, and other symptoms of anemia
• Improves oxygen delivery to tissues
• Reduces need for injectable erythropoiesis-stimulating agents
• Supports better quality of life in CKD patients

Side Effects

Common side effects may include:

• Nausea or vomiting
• Diarrhea or constipation
• Dizziness
• Hypertension (high blood pressure)
• Peripheral edema (swelling in limbs)

Serious adverse effects require immediate medical attention and close monitoring.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Regular monitoring of hemoglobin, iron status, and cardiovascular health is essential
• Use cautiously in patients with heart disease or uncontrolled hypertension
• Not recommended during pregnancy unless clearly necessary
• Inform your doctor about all concurrent medications
• Dose adjustments may be required based on response and safety

Storage

• Store below 30°C in a dry place
• Protect from light and moisture
• Keep out of reach of children.