Renesis Tablet 20 mg contains Roxadustat, an oral hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor used in the treatment of anemia associated with chronic kidney disease (CKD). It works by stimulating the body’s natural production of erythropoietin, improving red blood cell formation and helping increase hemoglobin levels without the need for injectable therapies.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Roxadustat 20 mg

Mechanism of Action

Roxadustat works by stabilizing hypoxia-inducible factor (HIF), leading to:

• Increased endogenous erythropoietin production in the kidneys
• Enhanced iron absorption and utilization
• Improved red blood cell production in the bone marrow
• Reduction of anemia associated with chronic kidney disease

This mechanism mimics the body’s natural response to low oxygen levels.

Indications

Renesis Tablet is indicated for:

• Anemia associated with chronic kidney disease (CKD) in adults
• Patients on dialysis and non-dialysis CKD cases (as prescribed by a specialist)

Dosage and Administration

• To be taken strictly under the supervision of a nephrologist
• Usually taken orally three times weekly or as directed
• Can be taken with or without food
• Dose is adjusted based on hemoglobin response and iron status
• Regular monitoring of hemoglobin levels is required

Benefits

• Increases hemoglobin levels effectively
• Reduces need for injectable erythropoiesis-stimulating agents (ESAs)
• Improves symptoms of anemia such as fatigue and weakness
• Enhances oxygen delivery to tissues
• Convenient oral therapy for CKD-related anemia

Side Effects

Common side effects may include:

• Nausea or vomiting
• Diarrhea or constipation
• Dizziness
• Hypertension (high blood pressure)
• Peripheral edema (swelling)

Serious side effects require medical attention and monitoring.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Regular monitoring of hemoglobin and iron levels is essential
• Use cautiously in patients with cardiovascular disease
• Not recommended during pregnancy unless clearly necessary
• Inform your doctor about all concurrent medications
• Dose adjustments may be required based on response

Storage

• Store below 30°C in a dry place
• Protect from light and moisture
• Keep out of reach of children.