Renesis Tablet 50 mg contains Roxadustat, an oral hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor used for the treatment of anemia associated with chronic kidney disease (CKD). It helps stimulate the body’s natural erythropoiesis process, increasing hemoglobin levels and improving symptoms of anemia such as fatigue and weakness. This higher-strength formulation is used when a stronger therapeutic response is required under specialist supervision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Roxadustat 50 mg

Mechanism of Action

Roxadustat works by stabilizing hypoxia-inducible factor (HIF), leading to:

• Increased endogenous erythropoietin production in the kidneys
• Enhanced iron absorption from the gastrointestinal tract
• Improved iron utilization for red blood cell formation
• Stimulation of erythropoiesis (RBC production) in bone marrow

This mechanism helps correct anemia in chronic kidney disease in a physiologic manner.

Indications

Renesis Tablet 50 mg is indicated for:

• Anemia associated with chronic kidney disease (CKD) in adults
• Patients undergoing dialysis or non-dialysis CKD management (as prescribed by a nephrologist)

Dosage and Administration

• To be taken strictly under medical supervision
• Usually administered orally three times weekly or as directed by a physician
• Can be taken with or without food
• Dose is adjusted based on hemoglobin response and iron status
• Regular monitoring of hemoglobin and iron parameters is essential

Benefits

• Increases hemoglobin levels effectively
• Reduces symptoms of anemia such as fatigue and weakness
• Improves oxygen delivery to tissues
• Decreases dependence on injectable erythropoiesis-stimulating agents
• Supports better quality of life in CKD patients

Side Effects

Common side effects may include:

• Nausea or vomiting
• Diarrhea or constipation
• Dizziness
• Hypertension
• Peripheral edema (swelling in limbs)

Serious adverse effects require immediate medical attention and regular monitoring.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Regular monitoring of hemoglobin, iron, and cardiovascular status is required
• Use cautiously in patients with heart disease or hypertension
• Not recommended during pregnancy unless clearly necessary
• Inform your doctor about all ongoing medications
• Dose adjustment may be required based on response and safety

Storage

• Store below 30°C in a dry place
• Protect from light and moisture
• Keep out of reach of children.