Seraflo Inhaler (25 mcg+125 mcg) combines Salmeterol, a long-acting bronchodilator, and Fluticasone Propionate, an inhaled corticosteroid, in a single inhalation device for the management of asthma and chronic obstructive pulmonary disease (COPD). This lower-dose formulation provides effective control of airway inflammation while ensuring smooth bronchodilation, making it suitable for patients requiring maintenance therapy or those whose symptoms are not fully controlled by corticosteroid monotherapy.

Salmeterol relaxes the muscles in the airways, providing prolonged bronchodilation, while Fluticasone Propionate reduces inflammation, swelling, and mucus in the airways. Together, they offer both symptom relief and long-term protection, helping prevent asthma attacks, reduce wheezing, and improve overall lung function.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Salmeterol 25 mcg per puff

• Fluticasone Propionate 125 mcg per puff

Mechanism of Action

Seraflo Inhaler works through a dual mechanism:

1. Salmeterol (Long-Acting β2-Agonist):

   • Binds to β2-adrenergic receptors in the bronchial smooth muscle

   • Relaxes airway muscles, leading to bronchodilation

   • Provides long-lasting relief from bronchospasm, wheezing, and shortness of breath

2. Fluticasone Propionate (Inhaled Corticosteroid):

   • Reduces airway inflammation and swelling

   • Suppresses the release of inflammatory mediators

   • Prevents airway remodeling and decreases the frequency of exacerbations

The combination ensures immediate relief from bronchospasm while also addressing the underlying inflammatory component of asthma and COPD.

Indications

Seraflo Inhaler (25 mcg+125 mcg) is indicated for:

• Maintenance treatment of asthma in adults and adolescents not adequately controlled with inhaled corticosteroids alone

• Long-term management of COPD in patients with persistent symptoms

• Prevention of asthma attacks and reduction of exacerbations

• Patients requiring both bronchodilation and anti-inflammatory therapy

It is not recommended for acute asthma attacks; a short-acting bronchodilator should be used in emergencies.

Dosage and Administration

• The usual dose is one inhalation twice daily (morning and evening) or as prescribed by a physician.

• Shake the inhaler well before use.

• Exhale fully, place the mouthpiece in the mouth, inhale deeply while pressing the canister, and hold the breath for 10 seconds before exhaling.

• Rinse the mouth with water after each use to reduce the risk of oral thrush.

Consistent use is essential for optimal control of asthma and COPD symptoms.

Benefits

• Reduces airway inflammation and bronchospasm

• Improves breathing and exercise tolerance

• Decreases the frequency and severity of asthma attacks

• Combines long-acting bronchodilation with corticosteroid protection

• Convenient inhaler for targeted delivery to the lungs

Precautions

• Not for relief of acute asthma attacks

• Use cautiously in patients with heart disease, high blood pressure, diabetes, or thyroid disorders

• Monitor for systemic corticosteroid effects with long-term use

• Consult a physician before use during pregnancy or breastfeeding

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects may include:

• Oral thrush (candidiasis)

• Throat irritation or hoarseness

• Tremors or palpitations

• Headache or mild dizziness

Rare but serious side effects:

• Severe allergic reactions

• Paradoxical bronchospasm

• Cardiovascular effects such as arrhythmia or hypertension

Storage

Store below 30°C in a dry, cool place, protected from sunlight. Keep the mouthpiece clean and capped when not in use. Keep out of reach of children.

Seraflo Inhaler (25 mcg+125 mcg) provides effective, long-term management of asthma and COPD by combining Salmeterol and Fluticasone Propionate, improving lung function, reducing exacerbations, and enhancing quality of life.