Telisa Plus Tablet 80 mg+12.5 mg is a potent combination antihypertensive medication containing Telmisartan 80 mg, an angiotensin II receptor blocker (ARB), and Hydrochlorothiazide 12.5 mg, a thiazide diuretic. This combination is designed for patients who require enhanced blood pressure control that cannot be achieved with monotherapy.

Telmisartan works by blocking the effects of angiotensin II, a hormone that causes blood vessels to constrict, thereby relaxing the vessels and lowering blood pressure. Hydrochlorothiazide promotes the excretion of sodium and water through the kidneys, reducing blood volume. Together, these two mechanisms provide effective and sustained blood pressure reduction, while also offering cardiovascular and renal protective benefits. The once-daily dosing regimen improves patient compliance and convenience for long-term therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Telisa Plus Tablet 80 mg+12.5 mg is indicated for:

• Essential hypertension in adults who require more potent blood pressure reduction

• Combination therapy for patients inadequately controlled with an ARB or thiazide alone

• Cardiovascular risk reduction, including prevention of stroke, heart attack, and other vascular complications

• Renal protection in patients at risk of kidney damage associated with long-standing hypertension

This medication is intended for chronic blood pressure management, not for immediate relief of hypertensive emergencies.

Mechanism of Action

Telisa Plus combines two complementary mechanisms:

• Telmisartan (ARB): Blocks angiotensin II from binding to AT1 receptors in the vascular smooth muscle, causing vasodilation, reduced aldosterone secretion, and lower systemic blood pressure

• Hydrochlorothiazide (Thiazide Diuretic): Increases renal excretion of sodium and water, reducing blood volume and peripheral resistance

• Combined effect: Synergistic blood pressure reduction with additional cardiovascular and renal protection

This dual mechanism ensures more consistent and effective control of hypertension compared to monotherapy.

Dosage and Administration

• The usual adult dose is one tablet orally once daily, with or without food

• Tablets should be swallowed whole with water

• Dose adjustments may be required in patients with renal or hepatic impairment

• Regular monitoring of blood pressure, kidney function, and electrolytes is recommended, particularly potassium and sodium

• Consistent daily use is critical for maintaining target blood pressure and preventing cardiovascular complications

Precautions and Warnings

• Pregnancy: Avoid use during the second and third trimesters due to potential fetal harm

• Use cautiously in patients with renal impairment, liver dysfunction, or electrolyte disturbances

• Hydrochlorothiazide may increase photosensitivity; avoid excessive sunlight or use sun protection

• May cause dizziness, especially during initiation or dose adjustment; avoid driving or operating machinery until effects are known

• Inform your healthcare provider about all medications, including NSAIDs, potassium supplements, or other diuretics, to prevent interactions

Side Effects

Telisa Plus Tablet 80 mg+12.5 mg is generally well tolerated. Common side effects may include:

• Dizziness or lightheadedness

• Headache or fatigue

• Mild gastrointestinal disturbances such as nausea or upset stomach

• Electrolyte imbalances, including low sodium or potassium changes

• Rare side effects: hypotension, kidney function changes, allergic reactions, or swelling

Seek immediate medical attention if severe dizziness, swelling, shortness of breath, or unusual symptoms occur.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

Store below 30°C in a cool, dry place, protected from light and moisture. Keep out of reach of children.

Telisa Plus Tablet 80 mg+12.5 mg provides strong, once-daily blood pressure control, combining two complementary mechanisms for enhanced efficacy, cardiovascular protection, and renal safety in patients requiring combination therapy.