Tenoren Plus Tablet combines Atenolol (50 mg), a selective beta-1 blocker, with Chlorthalidone (25 mg), a thiazide-like diuretic, to provide effective blood pressure control. This fixed-dose combination is designed for patients who require dual therapy to manage hypertension that is not adequately controlled with a single agent.

Atenolol lowers heart rate and cardiac workload, while Chlorthalidone promotes excretion of excess sodium and water, reducing blood volume. Together, they work synergistically to maintain optimal blood pressure and reduce the risk of cardiovascular complications.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Tenoren Plus Tablet is indicated for:

• Hypertension (high blood pressure)
• Patients requiring combination therapy for better blood pressure control
• Prevention of cardiovascular complications such as heart attack and stroke
• Management of edema associated with hypertension

Mechanism of Action

• Atenolol: A selective beta-1 blocker that slows heart rate and reduces the force of cardiac contraction, lowering blood pressure and decreasing myocardial oxygen demand.
• Chlorthalidone: A thiazide-like diuretic that increases urinary excretion of sodium and water, decreasing blood volume and vascular resistance.

The combination provides comprehensive blood pressure control through complementary mechanisms.

Dosage and Administration

• The usual dose is one tablet daily or as prescribed by a physician.
• Take the tablet with or without food at the same time each day for optimal effect.
• Regular monitoring of blood pressure and electrolyte levels is recommended.
• Do not stop therapy abruptly without consulting a doctor.

Benefits

• Dual mechanism ensures better blood pressure control
• Reduces strain on the heart and vascular system
• Helps prevent heart attack, stroke, and other cardiovascular events
• Convenient fixed-dose combination improves patient compliance
• Supports long-term cardiovascular health

Side Effects

Common side effects may include:

• Dizziness or lightheadedness
• Fatigue or weakness
• Cold hands and feet
• Increased urination
• Electrolyte imbalance (e.g., low potassium)

Serious but rare side effects:

• Severe hypotension
• Worsening heart failure
• Allergic reactions
• Gout or kidney-related issues

Seek immediate medical attention if severe symptoms occur.

Precautions and Warnings

• Use cautiously in patients with asthma, COPD, or severe bradycardia.
• Monitor kidney function and electrolyte levels during therapy.
• Avoid abrupt discontinuation to prevent rebound hypertension or cardiac events.
• May mask signs of hypoglycemia in diabetic patients.
• Pregnant and breastfeeding women should consult a physician before use.
• Adjust dosage in patients with renal or hepatic impairment.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Tenoren Plus Tablet may interact with:

• Other antihypertensive agents
• NSAIDs (may reduce efficacy)
• Antiarrhythmic drugs
• Lithium or digoxin
• Corticosteroids or other medications affecting electrolytes

Inform your healthcare provider about all medications and supplements you are taking.

Storage

• Store below 30°C in a cool, dry place
• Protect from light and moisture
• Keep out of reach of children.