Tetrabez Tablet 25 mg contains Tetrabenazine, a medication used to manage movement disorders caused by neurological conditions. It is primarily prescribed for the treatment of chorea associated with Huntington’s disease, a genetic disorder that causes progressive degeneration of nerve cells in the brain. This condition often leads to involuntary, irregular, and uncontrollable body movements.

Tetrabez works by regulating certain chemical messengers in the brain that influence motor control. By reducing excessive nerve signaling responsible for abnormal movements, it helps control involuntary muscle activity and improves coordination. The medicine is commonly used when patients require stronger or more sustained control of symptoms compared to lower doses.

With proper medical supervision, Tetrabez Tablet 25 mg can significantly improve the quality of life for patients suffering from hyperkinetic movement disorders by reducing the frequency and severity of uncontrolled movements.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Tetrabenazine

• Strength: 25 mg per tablet

• Dosage Form: Oral tablet

• Pharmacological Class: Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor

Mechanism of Action

Tetrabenazine works by inhibiting vesicular monoamine transporter type 2 (VMAT2), a protein responsible for transporting neurotransmitters such as dopamine, serotonin, and norepinephrine into storage vesicles within nerve cells.

By blocking VMAT2, tetrabenazine reduces the release of dopamine in the brain. Excess dopamine activity is associated with abnormal involuntary movements. Lowering dopamine levels helps control chorea and other hyperkinetic movement disorders, leading to improved motor stability.

Indications

Tetrabez Tablet 25 mg is indicated for:

• Treatment of chorea associated with Huntington’s disease

• Management of hyperkinetic movement disorders

• Control of involuntary movements related to neurological conditions

Dosage and Administration

• The dosage should be determined by a qualified healthcare professional based on the patient’s medical condition and response to treatment.

• Treatment generally begins with a low dose, which may be gradually increased to achieve optimal therapeutic benefit.

• The tablet should be swallowed whole with water.

• It may be taken with or without food.

• Patients should strictly follow their physician’s instructions and should not change the dose without medical advice.

Benefits

• Helps reduce involuntary and uncontrolled movements

• Improves motor coordination and daily functioning

• Provides effective management of Huntington’s disease-related chorea

• Supports better quality of life for patients with movement disorders

Possible Side Effects

Some patients may experience side effects while taking Tetrabez Tablet.

Common side effects include:

• Drowsiness

• Fatigue

• Insomnia

• Nausea

• Anxiety or mood changes

Serious but less common side effects may include:

• Severe depression

• Suicidal thoughts or behavior

• Parkinson-like symptoms

• Irregular heartbeat

Patients should consult their doctor if any side effects persist or worsen.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use with caution in patients with a history of depression or psychiatric illness.

• Not recommended for individuals with untreated or severe depression.

• Inform your doctor about all medications being taken, particularly antidepressants, antipsychotics, or MAO inhibitors.

• Patients should be closely monitored during treatment for changes in mood or behavior.

• Avoid driving or operating machinery if the medicine causes drowsiness or dizziness.

Storage

• Store in a cool and dry place below 30°C.

• Protect from light and moisture.

• Keep out of reach of children.