Tevirax Tablet 25 mg contains Tenofovir Alafenamide (TAF), a potent antiviral medication used for the treatment of chronic hepatitis B virus (HBV) infection. It belongs to the class of nucleotide reverse transcriptase inhibitors (NRTIs) and works by blocking viral replication within liver cells.

Compared to older formulations, Tenofovir Alafenamide is more efficiently delivered to the liver, allowing lower doses while maintaining efficacy. This reduces potential side effects on kidneys and bones, making it safer for long-term use.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Tevirax Tablet is indicated for:

• Chronic hepatitis B infection in adults and adolescents (≥12 years)
• Patients requiring antiviral therapy to prevent progression of liver disease
• Individuals at risk of developing cirrhosis or hepatocellular carcinoma
• Patients with compensated or decompensated liver disease

Mechanism of Action

Tenofovir Alafenamide is a prodrug that converts to its active form, tenofovir diphosphate, inside hepatocytes. It works by:

• Inhibiting HBV reverse transcriptase
• Blocking viral DNA synthesis
• Suppressing viral replication and reducing liver inflammation

This targeted action results in sustained viral suppression with improved safety compared to older tenofovir formulations.

Dosage and Administration

• The standard adult dose is 25 mg once daily, taken orally with or without food.
• Swallow the tablet whole; do not crush, split, or chew.
• Therapy duration depends on viral load, liver function, and patient response; long-term therapy is often necessary.
• Dose adjustment may be required in patients with renal impairment.

Benefits

• Potent suppression of HBV replication
• Reduced risk of kidney and bone toxicity compared to older tenofovir formulations
• Improves liver function and decreases liver inflammation
• Lowers risk of cirrhosis and hepatocellular carcinoma
• Convenient once-daily dosing enhances patient adherence

Side Effects

Common side effects may include:

• Headache
• Nausea
• Fatigue
• Mild gastrointestinal discomfort

Serious but rare side effects:

• Kidney problems or changes in kidney function
• Lactic acidosis
• Severe liver dysfunction
• Allergic reactions

Seek medical attention if severe symptoms occur.

Precautions and Warnings

• Monitor liver and kidney function before and during therapy.
• Use caution in patients with pre-existing kidney disease or liver impairment.
• Abrupt discontinuation may result in HBV flare; always consult a physician before stopping.
• Pregnancy and breastfeeding should only use under medical supervision.
• Inform your healthcare provider about all medications and supplements you are taking.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Tevirax Tablet may interact with:

• Other antiviral medications
• Nephrotoxic drugs
• Drugs affecting kidney function or liver metabolism

Always inform your healthcare provider about all medications, supplements, or herbal products in use.

Storage

• Store below 25°C in a cool, dry place
• Protect from light and moisture
• Keep out of reach of children.