Tofen Eye Drop 0.03% contains Ketotifen Fumarate, a potent antiallergic agent with dual action. It acts as a non-competitive histamine (H1) receptor antagonist and a mast cell stabilizer. By blocking H1 receptors, Ketotifen reduces the effects of histamine released during allergic reactions, thereby alleviating itching and redness.

In addition, Ketotifen inhibits the release of inflammatory mediators such as histamine, leukotrienes, and prostaglandins from mast cells involved in type I hypersensitivity reactions. It also suppresses eosinophil activation and chemotaxis and inhibits platelet-activating factor (PAF). Through these mechanisms, Tofen Eye Drop provides both immediate symptomatic relief and long-term control of allergic inflammation in the eye.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Dosage & Administration

• Adults and children (≥3 years): One drop into the affected eye(s) twice daily, usually every 8–12 hours, or as directed by the physician.

• The drops should be used regularly for optimal preventive benefit.

• Avoid touching the dropper tip to any surface to prevent contamination.

• Contact lenses should be removed before application and may be reinserted after at least 15 minutes.

Drug Interactions

No clinically significant drug interactions have been reported with ophthalmic Ketotifen. However, if other eye medications are being used, a gap of at least 5–10 minutes should be maintained between applications.

Contraindications

Tofen Eye Drop 0.03% is contraindicated in patients with known hypersensitivity to Ketotifen Fumarate or any of the excipients used in the formulation.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Side Effects

Tofen Eye Drop is generally well tolerated. Mild and transient side effects may include:

• Eye irritation or burning sensation after instillation

• Mild conjunctival redness

• Dry eyes

• Temporary blurred vision

These effects usually resolve spontaneously and do not require discontinuation of therapy.

Pregnancy & Lactation

There is limited data regarding the use of ophthalmic Ketotifen during pregnancy and lactation. Although systemic absorption is minimal, Tofen Eye Drop should be used during pregnancy or breastfeeding only if clearly needed and under medical supervision.

Precautions & Warnings

• For ophthalmic use only; not for injection or oral use.

• Patients should avoid driving or operating machinery immediately after instillation if temporary blurred vision occurs.

• Long-term use should be under the guidance of a healthcare professional.

• If signs of eye infection, severe pain, or vision changes occur, treatment should be discontinued and medical advice sought.

Overdose

Overdose with Tofen Eye Drop is unlikely due to its topical use. Accidental oral ingestion is not expected to cause serious effects but should be managed symptomatically if necessary.

Storage Conditions

Store below 30°C, protected from light. Do not freeze. Keep the bottle tightly closed and out of the reach of children.