TPS Injection 500 mg contains Thiopental Sodium, a short-acting barbiturate used as a general anesthetic agent. It is primarily used for the induction of anesthesia before surgical procedures and in certain emergency settings where rapid sedation is required. It produces quick onset of unconsciousness and is administered only in controlled hospital environments.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each vial contains:

• Thiopental Sodium 500 mg

Indications

TPS Injection is indicated for:

• Induction of general anesthesia
• Short surgical procedures requiring rapid anesthesia
• Emergency control of seizures (status epilepticus, as prescribed)
• Reduction of intracranial pressure in neurosurgical settings
• Pre-anesthetic sedation (as directed by anesthesiologist)

Mechanism of Action

Thiopental Sodium is a barbiturate that enhances the activity of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter in the central nervous system. This leads to rapid depression of brain activity, resulting in loss of consciousness, sedation, and anesthesia.

Dosage & Administration

• Must be administered only by an anesthesiologist or trained healthcare professional
• Given via slow intravenous injection after proper reconstitution
• Dosage is strictly individualized based on patient condition, weight, and surgical requirement
• Requires continuous monitoring of respiratory and cardiovascular function
• For hospital use only

Precautions

• Should only be used in a fully equipped resuscitation setting
• Risk of respiratory depression and hypotension
• Use with caution in patients with cardiovascular instability
• Not suitable for outpatient or self-administration
• Avoid in patients with porphyria
• Requires airway support facilities during use

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Side Effects

Possible side effects include:

• Respiratory depression or apnea
• Hypotension
• Bradycardia
• Drowsiness or prolonged sedation
• Injection site irritation or pain
• Allergic reactions (rare)

Immediate medical support is required in case of respiratory or cardiovascular complications.

Storage

• Store below 25–30°C in a cool, dry place
• Protect from light
• Do not freeze
• Reconstituted solution should be used immediately
• Keep out of reach of children.