Amoxicillin is a semi-synthetic penicillin antibiotic that exerts its bactericidal action by inhibiting bacterial cell wall synthesis. Many bacteria, however, produce beta-lactamase enzymes that render amoxicillin ineffective. Clavulanic acid acts as a beta-lactamase inhibitor, protecting amoxicillin from enzymatic degradation and thereby extending its antibacterial spectrum. The combination ensures reliable activity against both beta-lactamase–producing and non-producing organisms.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Tyclav BID Suspension is indicated for the treatment of a wide range of bacterial infections, including:

• Upper respiratory tract infections such as sinusitis, tonsillitis, pharyngitis, and otitis media

• Lower respiratory tract infections including bronchitis and community-acquired pneumonia

• Urinary tract infections such as cystitis

• Skin and soft tissue infections including cellulitis and wound infections

• Dental infections caused by susceptible organisms

The suspension is particularly suitable for children and patients who have difficulty swallowing tablets.

Dosage and Administration

The dosage of Tyclav BID Suspension should be determined by a healthcare professional based on the patient’s age, body weight, severity of infection, and renal function. It is usually administered twice daily. The suspension should be taken at the start of a meal to improve absorption and minimize gastrointestinal side effects. The full course of therapy should be completed as prescribed, even if symptoms improve earlier.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Benefits and Features

• Broad-spectrum antibacterial activity

• Effective against beta-lactamase–producing bacteria

• Convenient twice-daily dosing regimen

• Palatable oral suspension suitable for pediatric use

• Proven efficacy in common community-acquired infections

Precautions and Warnings

• Contraindicated in patients with known hypersensitivity to penicillins, cephalosporins, or beta-lactam antibiotics

• Use with caution in patients with hepatic impairment or a history of cholestatic jaundice associated with amoxicillin-clavulanic acid

• Prolonged use may result in overgrowth of non-susceptible organisms

• Dose adjustment may be required in renal impairment

Possible Side Effects

Common side effects include diarrhea, nausea, vomiting, abdominal discomfort, and skin rash. Less commonly, liver enzyme elevations or allergic reactions may occur. If severe diarrhea, hypersensitivity reactions, or other serious adverse effects develop, medical advice should be sought immediately.

Storage Instructions

Before reconstitution, store in a cool and dry place. After reconstitution, keep the suspension refrigerated if advised, shake well before each use, and use within the recommended period. Keep out of reach of children.