Upanib 15 mg contains Upadacitinib, an oral Janus kinase (JAK) inhibitor used for the management of moderate to severe autoimmune conditions. It is designed to selectively inhibit JAK1, a key enzyme involved in the inflammatory process, thereby reducing overactive immune responses that cause tissue damage. Upanib 15 mg provides a convenient, once-daily oral therapy option for patients who require long-term immunomodulatory treatment.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active ingredient: Upadacitinib 15 mg

• Dosage form: Oral tablet

Therapeutic Class

• Janus kinase (JAK) inhibitor

• Immunomodulatory agent

Mechanism of Action

Upadacitinib selectively inhibits the activity of JAK1, an enzyme that transmits signals from cytokines and growth factors involved in immune function and inflammation. By blocking JAK1-mediated signaling pathways, Upanib 15 mg reduces the production of pro-inflammatory cytokines, helping control symptoms such as joint pain, swelling, and tissue damage in autoimmune disorders. This selective inhibition allows for targeted disease control while minimizing effects on other pathways.

Indications

Upanib 15 mg is indicated for the treatment of:

• Moderate to severe rheumatoid arthritis (RA) in adult patients with inadequate response or intolerance to one or more disease-modifying antirheumatic drugs (DMARDs)

• Psoriatic arthritis (PsA) to reduce symptoms and improve physical function

• Atopic dermatitis (AD) in adults and adolescents when conventional therapies are insufficient, based on clinical guidelines

• Other autoimmune or inflammatory conditions as determined by a specialist

Dosage and Administration

• The recommended dose is 15 mg once daily, taken orally with or without food.

• Dose adjustments may be required for patients with moderate or severe renal or hepatic impairment.

• Regular monitoring of blood counts, liver enzymes, and lipid levels is advised during therapy.

• Patients should follow their healthcare provider’s instructions and not discontinue therapy abruptly.

Benefits and Features

• Convenient once-daily oral therapy

• Targeted JAK1 inhibition for effective symptom control

• Helps reduce joint pain, swelling, and inflammation

• May slow disease progression and improve physical function

• Suitable for long-term management under medical supervision

Precautions and Warnings

• May increase the risk of serious infections; patients should be evaluated for latent infections before starting therapy.

• Monitor for blood clots, malignancies, and cardiovascular events during treatment.

• Not recommended during pregnancy or breastfeeding unless clearly advised by a healthcare professional.

• Patients should inform their doctor about all medications and medical conditions before starting therapy.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Side Effects

Common side effects include upper respiratory tract infections, nausea, headache, and elevated liver enzymes. Serious adverse reactions may include serious infections, blood disorders, or cardiovascular complications, which require immediate medical attention.

Storage

• Store below 30°C

• Protect from moisture and light

• Keep out of reach of children

Upanib 15 mg offers a modern, targeted approach for managing autoimmune diseases. When used under proper medical guidance, it provides effective symptom relief, improved quality of life, and long-term disease control.