Ursotab Tablet 300 mg (Ursodeoxycholic Acid)

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Ursotab Tablet 300 mg contains Ursodeoxycholic Acid (UDCA), a naturally occurring bile acid used in the treatment of liver and gallbladder disorders. It works by improving bile flow, reducing toxic bile acids, and protecting liver cells from damage.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Ursotab Tablet is indicated for:

  • Gallstones (cholesterol gallstones in functioning gallbladder)
  • Primary biliary cholangitis (PBC)
  • Cholestatic liver diseases
  • Fatty liver disease (as supportive therapy)
  • Intrahepatic cholestasis of pregnancy (under medical supervision)
  • Liver disorders associated with bile flow impairment

Mechanism of Action

Ursodeoxycholic Acid works through multiple actions:

  • Reduces cholesterol absorption and secretion into bile
  • Dissolves cholesterol-rich gallstones
  • Protects liver cells from toxic bile acids
  • Improves bile flow (choleretic effect)
  • Reduces inflammation in liver tissue

Dosage and Administration

  • The usual dose is 10–15 mg/kg/day, divided into 2–3 doses or as prescribed
  • Tablets should be taken with food or after meals
  • Swallow with water without crushing
  • Duration of therapy may range from months to long-term use depending on condition

Benefits

  • Helps dissolve cholesterol gallstones without surgery in selected cases
  • Improves liver function and bile flow
  • Protects liver cells from damage
  • Reduces symptoms of cholestatic liver disease
  • Supports long-term liver health management

Side Effects

Common side effects may include:

  • Diarrhea
  • Abdominal discomfort
  • Nausea
  • Bloating

Rare side effects:

  • Allergic reactions
  • Elevated liver enzymes (temporary in some cases)
  • Skin rash or itching

Precautions and Warnings

  • Not effective for pigment or calcified gallstones
  • Use cautiously in patients with severe liver impairment
  • Regular monitoring of liver function is recommended
  • Not recommended in complete biliary obstruction
  • Use during pregnancy only if clearly advised by a physician
  • Long-term therapy may be required for chronic conditions

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Ursotab Tablet may interact with:

  • Cholestyramine and other bile acid sequestrants (reduce absorption)
  • Antacids containing aluminum hydroxide
  • Estrogen-containing oral contraceptives (may reduce effectiveness)

Maintain appropriate dosing intervals when used with other medications.

Storage

  • Store below 30°C in a dry place
  • Protect from moisture and light
  • Keep out of reach of children. 

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Ursotab Tablet 300 mg (Ursodeoxycholic Acid)
Ursotab Tablet 300 mg (Ursodeoxycholic Acid)
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