Valporin CR Tablet 300 mg contains Sodium Valproate, a controlled-release formulation designed for the management of epilepsy, bipolar disorder, and certain seizure-related disorders. The controlled-release (CR) mechanism allows the medication to be released gradually, maintaining steady blood levels, reducing dosing frequency, and improving treatment adherence.

Valporin CR helps prevent seizures, stabilizes mood in bipolar disorder, and supports long-term neurological and psychiatric health. It is suitable for adults and older children who require extended therapeutic action for optimal symptom control.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Seizure Management: Reduces frequency and severity of generalized, partial, and absence seizures.

• Mood Stabilization: Effective in controlling manic and mixed episodes in bipolar disorder.

• Controlled-Release Technology: Ensures stable plasma drug levels for longer duration and once-daily dosing convenience.

• Supports Long-Term Therapy: Safe for extended use under medical supervision.

• Enhanced Quality of Life: Reduces seizure episodes and stabilizes mood, improving daily functioning.

Mechanism of Action

Sodium Valproate works by:

• Increasing gamma-aminobutyric acid (GABA) levels in the brain, calming overactive neurons.

• Stabilizing electrical activity in neurons to prevent abnormal firing, controlling seizures.

• Modulating neurotransmitter activity to maintain mood stability in bipolar disorder.

The controlled-release formulation provides consistent drug levels, reducing the risk of breakthrough seizures or mood fluctuations.

Indications

Valporin CR Tablet 300 mg is indicated for:

• Epilepsy: generalized, partial, and absence seizures

• Bipolar disorder: treatment and maintenance of manic episodes

• Migraine prophylaxis (as prescribed by a physician)

• Other neurological or psychiatric conditions requiring anticonvulsant therapy

Dosage and Administration

• Dosage is individualized based on age, weight, and clinical condition.

• Typically taken once or twice daily, as directed by a physician.

• Swallow the tablet whole; do not crush or chew.

• Take with or after meals to minimize stomach irritation.

• Regular monitoring of liver function, blood counts, and plasma drug levels is recommended during therapy.

Precautions

• Avoid abrupt discontinuation to prevent seizure recurrence or mood destabilization.

• Use with caution in patients with liver disease, kidney impairment, or history of pancreatitis.

• Inform your doctor of all concurrent medications to avoid interactions.

• Pregnant or breastfeeding women should consult a physician before use.

• Report any unusual symptoms such as jaundice, persistent vomiting, or abdominal pain.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Side Effects

Common side effects may include:

• Nausea or mild gastrointestinal discomfort

• Tremors

• Weight gain

• Hair thinning

Rare but serious side effects include:

• Liver toxicity

• Pancreatitis

• Blood disorders (thrombocytopenia, anemia)

• Severe allergic reactions

Seek immediate medical attention if severe abdominal pain, jaundice, persistent vomiting, or unusual bleeding occurs.

Storage

Store in a cool, dry place below 25°C. Protect from light and moisture. Keep out of reach of children.