Vave Tablet 10 mg contains Domperidone Maleate, a prokinetic and antiemetic medication used to manage gastrointestinal motility disorders and relieve nausea and vomiting. Domperidone works by blocking dopamine receptors in the gut and brain, which enhances gastric emptying, improves intestinal movement, and prevents nausea.

Vave is commonly prescribed for conditions like gastroparesis, delayed stomach emptying, and nausea associated with medication or illness, providing quick and effective symptomatic relief.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Vave Tablet 10 mg is indicated for:

• Relief of nausea and vomiting of various causes
• Treatment of gastroparesis and delayed gastric emptying
• Management of functional dyspepsia with bloating, fullness, or early satiety
• Prevention of nausea and vomiting associated with medications such as chemotherapy

Mechanism of Action

Domperidone Maleate is a peripheral dopamine D2 receptor antagonist:

• Blocks dopamine receptors in the gastrointestinal tract, promoting smooth muscle contractions and gastric emptying
• Reduces signals from the gut to the vomiting center in the brain
• Increases esophageal and gastric motility, alleviating bloating and discomfort
• Provides antiemetic effects without significant central nervous system sedation

This dual action ensures rapid relief from both nausea and gastrointestinal motility issues.

Dosage and Administration

• Adults: 10 mg, 3–4 times daily, 15–30 minutes before meals
• For children, dosage is adjusted according to body weight and age
• Swallow the tablet with a full glass of water
• Avoid exceeding the recommended dose
• Use under physician supervision, especially in patients with heart or liver conditions

Benefits

• Rapid relief from nausea and vomiting
• Improves gastric emptying and gut motility
• Reduces bloating, fullness, and discomfort associated with digestive disorders
• Non-sedating, allowing patients to maintain normal daily activities
• Can be used alongside other treatments for chemotherapy-induced nausea

Side Effects

Common side effects may include:

• Dry mouth
• Abdominal cramps or mild diarrhea
• Headache or dizziness

Rare but serious side effects:

• Irregular heartbeats or palpitations
• Severe allergic reactions (rash, swelling, difficulty breathing)
• Extrapyramidal symptoms (rare)

Seek immediate medical attention if severe reactions or heart symptoms occur.

Precautions and Warnings

• Use with caution in patients with heart rhythm disorders or liver impairment
• Avoid in patients with known hypersensitivity to Domperidone
• Not recommended for long-term use without medical supervision
• Pregnancy and breastfeeding: only use if clearly indicated by a physician
• Monitor for signs of prolonged QT interval or cardiac issues in high-risk patients

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Domperidone may interact with:

• CYP3A4 inhibitors (may increase drug levels)
• Other medications that affect heart rhythm
• Antacids or medications that alter gastric pH (may affect absorption)

Always inform your healthcare provider about all medicines and supplements before starting therapy.

Storage

• Store below 25°C in a dry, cool place
• Protect from light and moisture
• Keep out of reach of children
• Do not use after the expiration date.