Vorifend Tablet 50 mg contains Voriconazole, a potent triazole antifungal used to treat systemic and serious fungal infections. It works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, thereby stopping fungal growth and promoting cell death.

This lower-strength formulation is useful for initiating therapy, dose adjustment, or pediatric patients requiring tailored dosing.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Voriconazole 50 mg

Mechanism of Action

Voriconazole acts by:

• Inhibiting fungal 14α-sterol demethylase: Prevents ergosterol synthesis, compromising fungal cell membranes

• Broad-spectrum antifungal effect: Effective against Candida, Aspergillus, and other pathogenic fungi

• Fungistatic and fungicidal activity: Reduces fungal growth and promotes clearance of infection

Indications

Vorifend Tablet 50 mg is indicated for:

• Treatment of systemic and invasive fungal infections

• Aspergillosis and candidemia

• Esophageal candidiasis

• Dose adjustment or pediatric therapy under medical supervision

Dosage and Administration

• Dose should be determined by a healthcare professional based on patient weight, age, and severity of infection

• Take orally with water, with or without food

• Adhere strictly to prescribed dosing schedule and duration

• Monitor liver function, kidney function, and electrolytes during prolonged therapy

Benefits of Vorifend Tablet

• Effective against a wide range of systemic fungal infections

• Flexible lower-dose option for dose titration or pediatric use

• Oral formulation ensures convenient administration

• Supports rapid recovery in immunocompromised or critically ill patients

Possible Side Effects

Common side effects may include:

• Visual disturbances (blurred vision, altered color perception)

• Nausea, vomiting, diarrhea

• Headache or dizziness

• Elevated liver enzymes

Rare serious side effects include liver toxicity, severe allergic reactions, or cardiac arrhythmias. Report any unusual symptoms promptly.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use only under strict medical supervision

• Caution in patients with liver or kidney impairment

• Avoid drugs that strongly interact with cytochrome P450 enzymes

• Monitor liver function, kidney function, and electrolytes regularly

• Not recommended during pregnancy unless benefits outweigh risks

• Keep out of reach of children

Storage

Store in a cool, dry place below 25°C, away from light and moisture. Keep the container tightly closed.

Vorifend Tablet 50 mg provides a safe and effective option for initiating therapy or adjusting doses in systemic fungal infections, ensuring optimal management of serious fungal conditions.