Xadu Tablet 50 mg contains Roxadustat, an advanced oral therapy used in the management of anemia associated with chronic kidney disease (CKD). Roxadustat belongs to the class of hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs) and works by stimulating the body’s natural pathways involved in red blood cell production. It offers a convenient and effective alternative to injectable erythropoiesis-stimulating agents, especially for patients requiring long-term anemia management.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active ingredient: Roxadustat 50 mg

• Dosage form: Tablet

• Route of administration: Oral

Mechanism of Action

Roxadustat inhibits prolyl hydroxylase enzymes that regulate hypoxia-inducible factors (HIFs). Inhibition of these enzymes stabilizes HIF proteins, leading to increased endogenous erythropoietin production in the kidneys and liver. This process enhances erythropoiesis in a physiological manner. Additionally, Roxadustat improves iron availability by reducing hepcidin levels, increasing intestinal iron absorption, and facilitating iron transport, all of which support efficient hemoglobin synthesis.

Indications

Xadu Tablet 50 mg is indicated for:

• Treatment of anemia in patients with chronic kidney disease

• Management of anemia in both dialysis-dependent and non-dialysis CKD patients, as prescribed

• Correction and maintenance of hemoglobin levels

• Reduction of anemia-related symptoms such as fatigue, dizziness, and reduced exercise tolerance

Dosage and Administration

The dosage of Xadu Tablet 50 mg should be determined by a healthcare professional based on patient weight, baseline hemoglobin levels, and therapeutic response. It is taken orally at scheduled intervals as directed. The tablet should be swallowed whole with water and can be taken with or without food. Regular monitoring of hemoglobin, iron status, and overall clinical condition is essential during treatment.

Benefits and Key Features

• Effective oral therapy for CKD-related anemia

• Promotes natural erythropoietin production

• Improves iron metabolism and utilization

• Helps maintain stable hemoglobin levels over time

• Reduces need for injectable anemia treatments

• Convenient dosing supports better patient adherence

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Safety and Precautions

Xadu Tablet 50 mg is generally well tolerated when used under medical supervision. Possible side effects may include headache, nausea, diarrhea, hypertension, hyperkalemia, or upper respiratory symptoms. Hemoglobin levels should be closely monitored to prevent excessive increases. Caution is advised in patients with cardiovascular disease, liver impairment, or a history of thromboembolic disorders. Use during pregnancy and breastfeeding should be based solely on medical advice.

Patients should inform their healthcare provider about all existing medical conditions and medications before initiating therapy.

Storage

Store below 30°C in a cool, dry place. Protect from light and moisture. Keep out of reach of children.

Xadu Tablet 50 mg from SK Pharma provides a reliable and patient-friendly option for the long-term management of anemia in chronic kidney disease, supporting improved quality of life through advanced oral treatment.