Xelobine Tablet 500 mg contains Capecitabine, an oral chemotherapy medicine used in the treatment of various types of cancers. It is a prodrug that is converted in the body into 5-fluorouracil (5-FU), an active anticancer agent that inhibits cancer cell growth and multiplication. Xelobine is commonly used in cancers of the breast, colon, and rectum, and may also be used in other solid tumors as part of combination chemotherapy regimens.

Capecitabine works by interfering with DNA synthesis in rapidly dividing cancer cells. It inhibits the enzyme thymidylate synthase, which is essential for DNA replication. This leads to disruption of cancer cell growth and eventual cell death. Because cancer cells divide more rapidly than normal cells, they are more affected by this mechanism.

Xelobine Tablet is taken orally, which provides convenience compared to intravenous chemotherapy. It is usually prescribed in cycles, allowing periods of treatment followed by rest periods to help the body recover. The dosage and schedule are carefully determined by an oncologist based on body surface area, type of cancer, and treatment response.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each film-coated tablet contains:

• Capecitabine USP 500 mg

Indications

Xelobine Tablet is indicated for:

• Metastatic breast cancer
• Colorectal cancer (colon and rectal cancer)
• Adjuvant therapy in colon cancer
• Gastric and other gastrointestinal cancers (as prescribed by oncologists)

How It Works

Capecitabine is converted into 5-fluorouracil (5-FU) in tumor tissues. 5-FU inhibits thymidylate synthase, blocking DNA synthesis and preventing cancer cell replication, ultimately leading to cancer cell death.

Dosage and Administration

The dosage should be strictly prescribed and monitored by a qualified oncologist.

• Usually taken twice daily after food
• Given in treatment cycles (e.g., 14 days on treatment followed by rest period, as prescribed)
• Dose depends on body surface area and clinical condition
• Tablets should be swallowed whole with water

Patients must strictly follow dosing schedules to avoid toxicity or reduced effectiveness.

Benefits of Xelobine Tablet

• Effective oral chemotherapy option
• Used in multiple types of solid tumors
• Convenient compared to injectable chemotherapy
• Targets rapidly dividing cancer cells
• Can be used in combination therapy protocols

Precautions

Use cautiously in:

• Bone marrow suppression
• Kidney or liver impairment
• Elderly patients
• Pregnancy and breastfeeding (strictly contraindicated unless essential)

Patients should be closely monitored for blood counts, liver function, and signs of toxicity during treatment.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects may include:

• Nausea and vomiting
• Diarrhea
• Fatigue
• Loss of appetite
• Hand-foot syndrome (redness, swelling, pain in palms and soles)
• Mouth ulcers
• Low white blood cell count

Serious side effects require immediate medical attention.

Storage

• Store below 30°C
• Protect from light and moisture
• Keep out of reach of children.