Xenapro Plus Tablet 375 mg+20 mg is a combination medication containing Naproxen Sodium, a nonsteroidal anti-inflammatory drug (NSAID), and Esomeprazole Magnesium, a proton pump inhibitor (PPI). This formulation is specifically designed to relieve pain and inflammation while protecting the stomach from NSAID-induced irritation.

Xenapro Plus 375 mg+20 mg is suitable for patients with arthritis, musculoskeletal pain, or other inflammatory conditions who are at risk of gastrointestinal complications from long-term NSAID use. By combining anti-inflammatory action with gastric protection, it offers effective and safer therapy for chronic pain management.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Effective Pain Relief: Reduces pain associated with arthritis, joint disorders, and musculoskeletal conditions.

• Anti-Inflammatory Action: Decreases swelling and inflammation for improved mobility.

• Gastrointestinal Protection: Esomeprazole minimizes the risk of NSAID-induced ulcers and heartburn.

• Convenient Once-Daily Therapy: Simplifies treatment by combining two medications into one tablet.

• Enhances Quality of Life: Provides pain control and gastric safety to support daily functioning.

Mechanism of Action

• Naproxen Sodium works by inhibiting cyclooxygenase (COX-1 and COX-2) enzymes, reducing prostaglandin production, which decreases pain, inflammation, and fever.

• Esomeprazole Magnesium suppresses gastric acid secretion by blocking proton pumps in the stomach lining, reducing the risk of ulcers and gastrointestinal irritation caused by NSAIDs.

Indications

Xenapro Plus Tablet 375 mg+20 mg is indicated for:

• Osteoarthritis and Rheumatoid Arthritis

• Musculoskeletal pain and inflammation

• Patients at risk of NSAID-related gastric ulcers

• Other inflammatory conditions requiring NSAID therapy with gastric protection

Dosage and Administration

• Typically, take one tablet orally once daily, preferably 30–60 minutes before a meal, or as directed by a physician.

• Swallow the tablet whole with water; do not crush, chew, or break.

• Follow the prescribed dosage and duration carefully to ensure effectiveness and safety.

Precautions

• Use cautiously in patients with heart, kidney, or liver disease.

• Avoid alcohol and additional NSAIDs unless approved by your doctor.

• Inform your physician about all medications being taken to avoid interactions, especially anticoagulants, corticosteroids, or other NSAIDs.

• Pregnant or breastfeeding women should use only under medical supervision.

• Report any persistent stomach pain, heartburn, or unusual bleeding promptly.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Side Effects

Common side effects may include:

• Nausea, indigestion, or abdominal discomfort

• Headache or dizziness

• Bloating or gas

Rare but serious side effects:

• Gastrointestinal bleeding or ulcers

• Allergic reactions such as rash, itching, or swelling

• Cardiovascular events with long-term NSAID use

Seek immediate medical attention if severe side effects or signs of gastrointestinal bleeding occur.

Storage

Store in a cool, dry place below 25°C. Protect from light and moisture. Keep out of reach of children.