Starcef Capsule 400 mg contains Cefixime Trihydrate, a third-generation cephalosporin antibiotic used to treat a wide range of bacterial infections. It works by stopping bacterial growth through inhibition of cell wall synthesis. This higher-strength formulation is used in moderate to severe infections where stronger antibiotic coverage is required, as prescribed by a physician.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Cefixime Trihydrate equivalent to Cefixime 400 mg

Mechanism of Action

Cefixime binds to penicillin-binding proteins (PBPs) located inside the bacterial cell wall. This inhibits the final step of peptidoglycan synthesis, which is essential for bacterial cell wall integrity. As a result, the bacterial wall weakens and ruptures, leading to bacterial cell death. It is effective against many Gram-positive and Gram-negative bacteria.

Indications

Starcef Capsule 400 mg is indicated for the treatment of:

• Severe respiratory tract infections (bronchitis, pneumonia)
• Urinary tract infections (complicated and uncomplicated)
• Typhoid fever (as prescribed by a physician)
• Otitis media (ear infections)
• Gonococcal infections (uncomplicated cases)
• Other bacterial infections based on clinical judgment

Dosage and Administration

• The dosage should be prescribed by a qualified physician.
• Commonly taken once daily or divided into two doses depending on infection severity.
• Can be taken with or without food.
• Swallow whole with water; do not crush or chew.
• Complete the full course of treatment even if symptoms improve early.

Benefits

• Broad-spectrum antibacterial coverage
• Effective in moderate to severe bacterial infections
• Convenient oral once-daily dosing option
• Helps reduce infection symptoms and complications
• Suitable for outpatient and step-down therapy

Side Effects

Common side effects may include:

• Diarrhea
• Nausea
• Abdominal pain
• Indigestion
• Headache

Rare but serious side effects may include severe allergic reactions, blood disorders, or antibiotic-associated colitis. Seek immediate medical attention if severe symptoms occur.

Precautions and Warnings

• Use cautiously in patients allergic to cephalosporins or penicillins.
• Not effective against viral infections such as cold or flu.
• Use with caution in patients with kidney impairment.
• Inform your doctor if you are pregnant or breastfeeding.
• Prolonged use may lead to antibiotic resistance.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Starcef Capsule may interact with:

• Anticoagulants (e.g., warfarin)
• Probenecid (may increase cefixime levels)
• Other nephrotoxic drugs

Always inform your healthcare provider about all medications being taken.

Storage

• Store below 30°C in a cool, dry place
• Protect from light and moisture
• Keep out of reach of children.