Xitabin Tablet 500 mg contains Capecitabine, an oral chemotherapy medication used in the treatment of various types of cancer. It is a prodrug of 5-fluorouracil (5-FU), which becomes active inside tumor cells to stop their growth and division. This targeted activation helps improve effectiveness while reducing systemic exposure. Xitabin is commonly used under oncology supervision as part of combination or single-agent chemotherapy regimens.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Xitabin Tablet 500 mg is indicated for the treatment of:

• Metastatic colorectal cancer
• Adjuvant treatment of colon cancer
• Metastatic breast cancer (especially after standard therapy failure)
• Gastric (stomach) cancer, as prescribed
• Other solid tumors as determined by an oncologist

Mechanism of Action

Capecitabine is converted in the body into 5-fluorouracil (5-FU), particularly within tumor tissues. 5-FU interferes with DNA and RNA synthesis by inhibiting thymidylate synthase, an enzyme essential for DNA replication. This disruption prevents cancer cells from multiplying, leading to cell death and tumor growth suppression.

Dosage and Administration

• Dosage is determined by an oncologist based on body surface area (BSA), cancer type, and treatment protocol
• Usually taken orally twice daily after meals
• Swallow tablets whole with water
• Treatment is given in cycles with rest periods as prescribed
• Strict adherence to dosing schedule is essential for effectiveness
• Regular blood tests are required during therapy

Benefits

• Oral chemotherapy option, convenient for outpatient treatment
• Effective against colorectal, breast, and gastric cancers
• Targets rapidly dividing cancer cells
• Often used in combination chemotherapy regimens for improved outcomes
• Helps slow disease progression and reduce tumor size

Side Effects

Common side effects may include:

• Nausea and vomiting
• Diarrhea
• Fatigue and weakness
• Loss of appetite
• Hand-foot syndrome (redness, swelling, or pain in palms and soles)

Serious side effects:

• Severe diarrhea leading to dehydration
• Bone marrow suppression (low blood counts)
• Liver dysfunction
• Cardiac effects (rare chest pain or ischemia)
• Severe skin reactions

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use only under strict oncologist supervision
• Regular monitoring of blood counts and liver function is required
• Not recommended during pregnancy or breastfeeding
• Use effective contraception during treatment
• Dose adjustments may be required in kidney or liver impairment
• Report severe diarrhea or unusual symptoms immediately

Storage

• Store below 25°C
• Protect from moisture and light
• Keep out of reach of children.