A-Phenicol D Eye Drop is a combination ophthalmic preparation containing Dexamethasone 0.1% and Chloramphenicol 0.5%. It is designed for the treatment of inflammatory eye conditions associated with, or at risk of, bacterial infection. This dual-action formulation provides effective control of inflammation while simultaneously eliminating susceptible bacterial pathogens.

The combination of a corticosteroid and a broad-spectrum antibiotic makes A-Phenicol D Eye Drop particularly useful in managing ocular conditions where inflammation and infection coexist. It helps reduce redness, swelling, pain, and irritation while preventing or treating bacterial eye infections under proper medical supervision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each milliliter of eye drop contains:

• Dexamethasone BP 1 mg (0.1% w/v)

• Chloramphenicol BP 5 mg (0.5% w/v)

Therapeutic Class

• Ophthalmic corticosteroid and antibiotic combination

• Anti-inflammatory and antibacterial agent

Indications

A-Phenicol D Eye Drop is indicated for the treatment of steroid-responsive inflammatory eye conditions where bacterial infection is present or likely to occur, including:

Inflammatory Ocular Conditions

• Allergic conjunctivitis with secondary infection

• Anterior uveitis

• Inflammatory conditions of the conjunctiva, cornea, and anterior segment of the eye

Bacterial Eye Infections with Inflammation

• Bacterial conjunctivitis

• Blepharitis and blepharoconjunctivitis

• Post-operative eye inflammation with risk of infection

The use of this combination should be based on careful clinical evaluation to ensure appropriate indication.

Mechanism of Action

Dexamethasone is a potent corticosteroid that works by suppressing inflammatory responses in the eye. It inhibits the release of inflammatory mediators, thereby reducing redness, swelling, pain, and hypersensitivity reactions. This helps provide rapid symptomatic relief in inflammatory eye conditions.

Chloramphenicol is a broad-spectrum antibiotic that inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit. This action prevents bacterial growth and multiplication, allowing effective control of susceptible Gram-positive and Gram-negative organisms commonly responsible for ocular infections.

Together, these components provide comprehensive management of inflammation while treating or preventing bacterial infection.

Dosage and Administration

A-Phenicol D Eye Drop should be used exactly as prescribed by a healthcare professional. The recommended dosage and duration of therapy depend on the severity of the condition and patient response.

Before instillation, hands should be washed thoroughly. The dropper tip should not touch the eye or surrounding surfaces to avoid contamination. Patients are advised to complete the full course of treatment as prescribed, even if symptoms improve earlier.

Prolonged use should be avoided unless strictly monitored by an eye specialist.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Not recommended for patients with hypersensitivity to dexamethasone, chloramphenicol, or any component of the formulation.

• Prolonged use of corticosteroids may increase intraocular pressure, delay wound healing, or increase the risk of secondary infections.

• Use with caution in patients with glaucoma or a history of ocular hypertension.

• Contact lenses should generally be avoided during treatment unless advised by a healthcare professional.

Possible Side Effects

Possible side effects may include:

• Temporary burning or stinging sensation after application

• Eye irritation or redness

• Blurred vision for a short duration

Rare but serious effects such as increased intraocular pressure or allergic reactions require immediate medical attention.

Storage Conditions

Store below 25°C in a cool, dry place. Protect from light. Do not use beyond the recommended period after opening. Keep out of reach of children.