Amotrex Tablet 400 mg contains Metronidazole, a widely used antimicrobial agent effective against anaerobic bacteria and certain protozoal infections. It is commonly prescribed to treat gastrointestinal, gynecological, and dental infections, as well as skin and soft tissue infections. Metronidazole works by inhibiting the growth of harmful microorganisms, thereby helping the body fight infection efficiently.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Metronidazole 400 mg

Mechanism of Action

Metronidazole penetrates the bacterial and protozoal cells and interferes with their DNA synthesis. This disruption prevents the microorganisms from multiplying, ultimately leading to their death. It is particularly effective against anaerobic bacteria, which thrive in environments with low oxygen levels, such as the gastrointestinal tract and deep tissue infections.

Indications

Amotrex Tablet 400 mg is indicated for:

• Bacterial infections caused by anaerobic bacteria
• Protozoal infections such as amoebiasis and giardiasis
• Gastrointestinal infections including Helicobacter pylori-associated conditions
• Gynecological infections, including bacterial vaginosis
• Dental infections and periodontitis
• Skin and soft tissue infections

Dosage and Administration

• Adults: Typically 400 mg 2–3 times daily, depending on the type and severity of infection.
• The tablet should be taken orally with a full glass of water, preferably after meals to reduce stomach upset.
• Complete the full course of therapy as prescribed, even if symptoms improve early, to prevent recurrence and resistance.
• Dosage adjustments may be required in patients with liver impairment.

Benefits

• Rapidly targets and eliminates anaerobic bacteria and protozoa
• Relieves symptoms of infection such as pain, inflammation, and diarrhea
• Supports healing of infected tissues
• Prevents the spread of infection to other areas
• Convenient oral tablet for easy administration

Possible Side Effects

Common side effects may include:

• Nausea or vomiting
• Abdominal discomfort or diarrhea
• Metallic taste in the mouth
• Headache
• Dizziness

Rare side effects may include allergic reactions, neuropathy, or severe gastrointestinal disturbances. Seek medical attention if serious symptoms occur.

Precautions and Warnings

• Avoid alcohol consumption during treatment and for at least 48 hours after completion, as it may cause nausea, vomiting, and flushing.
• Use cautiously in patients with liver disease or neurological disorders.
• Not recommended during the first trimester of pregnancy unless clearly necessary.
• Consult a doctor if breastfeeding, as small amounts may pass into breast milk.
• Inform your healthcare provider about any history of blood disorders, seizures, or neuropathy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Amotrex Tablet may interact with:

• Warfarin (increases bleeding risk)
• Lithium
• Anticoagulants and certain antiepileptics
• Alcohol (may cause disulfiram-like reaction)

Always inform your doctor about all medications and supplements being taken.

Storage Instructions

• Store below 30°C in a dry place
• Protect from light and moisture
• Keep out of reach of children.