Anustat Ointment is a multi-ingredient topical preparation formulated for the management of anorectal disorders such as hemorrhoids, anal fissures, and associated inflammatory conditions. Each gram of Anustat contains cinchocaine 5 mg, hydrocortisone 5 mg, neomycin 10 mg, and esculin 10 mg, combining local anesthetic, anti-inflammatory, antibacterial, and venotonic properties to provide rapid relief from pain, itching, inflammation, and infection associated with anorectal conditions.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Class

Topical Anorectal Preparation / Local Anesthetic + Corticosteroid + Antibiotic + Venotonic

Indications

Anustat Ointment is indicated for:

• Symptomatic relief of pain, itching, and burning associated with hemorrhoids

• Inflammation and swelling of the anal region

• Secondary bacterial infection of the anorectal area

• Supportive therapy in anal fissures and minor anorectal trauma

• Improvement of venous tone and microcirculation in the anorectal region

Pharmacology and Mode of Action

Cinchocaine:
Cinchocaine is a local anesthetic that temporarily blocks nerve conduction, providing rapid relief from pain and discomfort in the anal region. Its action reduces irritation, burning, and itching, improving patient comfort.

Hydrocortisone:
Hydrocortisone is a mild corticosteroid that exhibits anti-inflammatory and antipruritic activity. It reduces edema, redness, and itching by inhibiting the release of inflammatory mediators from mast cells and other inflammatory cells.

Neomycin:
Neomycin is an aminoglycoside antibiotic effective against a broad spectrum of gram-negative bacteria. It helps prevent or treat secondary bacterial infections in the anorectal area, which can complicate hemorrhoids or fissures.

Esculin:
Esculin is a venotonic and vasoprotective agent derived from the horse chestnut plant. It strengthens venous walls, improves microcirculation, and reduces capillary permeability, contributing to decreased swelling and inflammation in hemorrhoidal tissues.

The combination of these four components allows Anustat to target multiple pathological processes simultaneously, providing pain relief, anti-inflammatory effects, antimicrobial protection, and improved venous function.

Dosage and Administration

• Apply a thin layer of ointment to the affected area 2–3 times daily, preferably after bowel movements and after cleaning the anal region.

• Gently massage the ointment into the skin to enhance absorption.

• Use for the duration recommended by a physician, usually until symptoms improve (typically 7–14 days).

• Wash hands before and after application to avoid contamination or accidental ingestion.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Contraindications

Anustat Ointment should not be used in:

• Patients with hypersensitivity to cinchocaine, hydrocortisone, neomycin, esculin, or any other excipients

• Individuals with viral, fungal, or tuberculosis infections of the anal region unless directed by a physician

• Severe systemic infections

Side Effects

Anustat Ointment is generally well tolerated. Possible side effects include:

• Local irritation, burning, or stinging at the site of application

• Allergic reactions such as rash, redness, or itching

• Rarely, prolonged use may cause skin thinning or secondary infections due to corticosteroid component

Precautions and Warnings

• Avoid contact with eyes or mucous membranes.

• Use under medical supervision in patients with diabetes, immune compromise, or chronic skin conditions.

• Prolonged or excessive use of topical corticosteroids may lead to systemic absorption and side effects.

Storage Conditions

Store in a cool, dry place below 30°C, protected from light and moisture. Keep out of reach of children.