Ariplat Injection 1 mg/ml contains Cisplatin, a platinum-based antineoplastic (anticancer) medicine used to treat a wide range of solid tumors. It works by damaging the DNA of cancer cells, preventing them from growing and dividing, ultimately leading to their destruction.

Cisplatin is widely used alone or in combination with other chemotherapy medicines for the treatment of testicular cancer, ovarian cancer, bladder cancer, lung cancer, head and neck cancers, cervical cancer, and several other malignancies. Due to its potent anticancer activity, treatment with Cisplatin requires close monitoring by experienced oncology specialists.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each ml contains:

• Cisplatin 1 mg

Indications

Ariplat Injection 1 mg/ml is indicated for the treatment of:

• Testicular cancer
• Ovarian cancer
• Bladder cancer
• Non-small cell and small cell lung cancer
• Head and neck cancers
• Cervical cancer
• Esophageal cancer
• Other advanced or metastatic solid tumors, as determined by an oncologist

How Ariplat Injection Works

Cisplatin binds to the DNA of cancer cells, forming cross-links that interfere with DNA replication and repair. As a result, cancer cells are unable to divide and eventually die.

Its therapeutic actions include:

• Inhibiting cancer cell growth
• Preventing tumor cell multiplication
• Reducing tumor progression
• Enhancing the effectiveness of combination chemotherapy regimens

Dosage and Administration

• Administer only under the supervision of a qualified oncologist or healthcare professional.
• Given as an intravenous (IV) infusion in a hospital or specialized oncology center.
• The dose depends on the patient's body surface area (BSA), kidney function, blood counts, and the type of cancer being treated.
• Adequate hydration is usually required before and after administration to reduce the risk of kidney damage.
• Regular monitoring of blood counts, kidney function, electrolytes, and hearing is essential throughout treatment.

Do not self-administer this medicine.

Benefits of Ariplat Injection

• Highly effective against a wide variety of solid tumors
• Helps slow or stop the growth of cancer cells
• Can be used alone or in combination with other chemotherapy medicines
• Plays an important role in curative and palliative cancer treatment
• Well-established chemotherapy agent with proven clinical effectiveness

Possible Side Effects

Common side effects may include:

• Nausea and vomiting
• Loss of appetite
• Fatigue
• Hair thinning or hair loss
• Low blood cell counts

Serious side effects may include:

• Kidney damage (nephrotoxicity)
• Hearing loss or ringing in the ears (ototoxicity)
• Peripheral neuropathy (numbness or tingling)
• Severe allergic reactions
• Electrolyte imbalances (low magnesium or potassium)
• Increased risk of infection due to bone marrow suppression

Seek immediate medical attention if you experience fever, severe allergic reactions, reduced urine output, hearing changes, or unusual bleeding.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• For intravenous use only under medical supervision.
• Adequate hydration before and after treatment is essential.
• Regular monitoring of kidney function, liver function, blood counts, electrolytes, and hearing is required.
• Inform your doctor if you have kidney disease, hearing problems, or nerve disorders.
• Effective contraception should be used during treatment and for a period after completion, as Cisplatin can harm an unborn baby.
• Breastfeeding is not recommended during treatment.
• Inform your healthcare provider about all medicines and supplements you are taking to minimize potential drug interactions.

Storage

• Store according to the manufacturer's recommendations, generally below 25°C.
• Protect from excessive heat and light.
• Do not freeze.
• Keep out of reach of children.
• Preparation and disposal should be performed by trained healthcare professionals using appropriate safety precautions.