Avloquin-H Tablet 200 mg contains Hydroxychloroquine Sulphate, a medication belonging to the antimalarial and immunomodulatory class. It is used for the treatment and prevention of malaria caused by susceptible Plasmodium species and also has applications in autoimmune conditions such as rheumatoid arthritis and lupus due to its immunomodulatory properties. Hydroxychloroquine works by interfering with the growth of Plasmodium parasites in red blood cells and modulating immune system activity.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Hydroxychloroquine Sulphate: 200 mg – an antimalarial and immunomodulatory agent

Mechanism of Action

• In malaria: Hydroxychloroquine enters infected red blood cells and disrupts heme detoxification, causing toxic heme accumulation that kills the parasite
• In autoimmune conditions: It modulates immune response, reducing inflammation and autoantibody activity
• Effective against Plasmodium vivax, Plasmodium malariae, Plasmodium ovale, and chloroquine-sensitive Plasmodium falciparum

Indications

Avloquin-H Tablet 200 mg is indicated for:

• Treatment of malaria caused by chloroquine-sensitive Plasmodium species
• Prevention of malaria in endemic regions
• Management of autoimmune disorders such as rheumatoid arthritis and systemic lupus erythematosus

Dosage and Administration

• Take orally with food or milk to reduce gastrointestinal discomfort
• Adult dose for malaria treatment: as prescribed by a physician
• For prophylaxis, a weekly dose may be recommended in endemic areas
• Pediatric dosing is weight-based and determined by a healthcare provider
• Complete the full course as prescribed to ensure therapeutic effectiveness

Benefits

• Effective in treating and preventing malaria
• Supports management of autoimmune conditions
• Convenient oral tablet for adults and older children
• Helps reduce malaria complications and autoimmune inflammation

Possible Side Effects

Common side effects:

• Nausea, vomiting, abdominal discomfort
• Headache or dizziness
• Mild skin rash or itching

Rare but serious side effects:

• Vision disturbances, including retinopathy
• Muscle weakness or cardiac rhythm abnormalities
• Severe allergic reactions (anaphylaxis)

Precautions and Warnings

• Contraindicated in patients with hypersensitivity to hydroxychloroquine or related compounds
• Use cautiously in patients with liver, kidney, or heart conditions
• Regular eye examinations are recommended during long-term therapy
• Not recommended for chloroquine-resistant malaria strains
• Inform your physician of all other medications being taken

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

• May interact with antacids, digoxin, amiodarone, and other QT-prolonging drugs
• Caution when used with other immunosuppressive medications

Storage Instructions

• Store at 15–30°C, protected from light and moisture
• Keep tablets in their original packaging
• Keep out of reach of children
• Do not use after the expiry date.