Xelopes Injection 40 mg/Vial contains Omeprazole, a proton pump inhibitor (PPI) used to reduce gastric acid secretion in patients who are unable to take oral medication or require rapid acid suppression. It is commonly used in hospital settings for the management of severe acid-related gastrointestinal disorders under the supervision of healthcare professionals.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Xelopes Injection 40 mg is indicated for:

• Severe gastroesophageal reflux disease (GERD)
• Peptic ulcer disease (gastric and duodenal ulcers)
• Upper gastrointestinal bleeding associated with acid-peptic disease
• Zollinger-Ellison syndrome
• Stress-related mucosal damage prophylaxis in critically ill patients
• Patients unable to take oral omeprazole therapy

Mechanism of Action

Omeprazole inhibits the hydrogen-potassium ATPase enzyme (proton pump) in gastric parietal cells. This blocks the final step of acid production in the stomach, leading to a rapid and sustained reduction in gastric acid secretion. As a result, it helps control acid-related symptoms and promotes healing of gastrointestinal lesions.

Dosage and Administration

• Administered intravenously by a healthcare professional only
• Dosage depends on the severity of the condition and clinical judgment
• Typically given once daily as an IV infusion or bolus injection
• Reconstitute and dilute as per manufacturer instructions before administration
• Use strict aseptic technique during preparation and administration

Benefits

• Provides rapid acid suppression in acute conditions
• Effective alternative when oral administration is not possible
• Helps manage severe GERD and ulcer-related complications
• Useful in hospital and emergency care settings
• Supports healing of gastrointestinal mucosal damage

Side Effects

Common side effects may include:

• Headache
• Nausea
• Abdominal discomfort
• Diarrhea or constipation
• Injection site reactions (pain, redness, swelling)

Rare but serious side effects:

• Severe allergic reactions
• Hypomagnesemia (low magnesium levels)
• Vitamin B12 deficiency with prolonged use
• Increased risk of gastrointestinal infections

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• For intravenous use only under medical supervision
• Use cautiously in patients with liver impairment
• Long-term therapy should be regularly monitored
• May interact with medications such as clopidogrel and certain antifungals
• Not recommended without proper clinical indication

Storage

• Store below 25°C
• Protect from light and moisture
• Reconstituted solution should be used immediately as directed
• Keep out of reach of children.