Avlosef Capsule 250 mg contains Cephradine, a first-generation cephalosporin antibiotic used to treat a wide variety of bacterial infections. It is known for its effectiveness against many Gram-positive and some Gram-negative bacteria, making it a reliable option for common infections.

Cephradine works by disrupting the formation of the bacterial cell wall, leading to bacterial cell death. Due to its proven safety profile and broad-spectrum activity, it is frequently prescribed in both mild and moderate infections.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Avlosef Capsule is indicated for the treatment of infections caused by susceptible organisms, including:

• Upper respiratory tract infections such as pharyngitis, tonsillitis, and sinusitis
• Lower respiratory tract infections including bronchitis and pneumonia
• Urinary tract infections (UTIs) such as cystitis and urethritis
• Skin and soft tissue infections including cellulitis, boils, and abscesses
• Ear infections (otitis media)
• Bone and joint infections in selected cases

Composition

• Active Ingredient: Cephradine
• Strength: 250 mg
• Dosage Form: Oral capsule

Mechanism of Action

Cephradine acts by inhibiting bacterial cell wall synthesis. It binds to penicillin-binding proteins (PBPs), preventing the formation of peptidoglycan, an essential component of the bacterial cell wall. This results in weakening of the bacterial structure and eventual cell lysis.

Dosage & Administration

• Adults: সাধারণত 1–2 g daily in divided doses (every 6–12 hours)
• Mild to moderate infections: Lower doses may be sufficient
• Children: সাধারণত 25–50 mg/kg/day in divided doses

Administration guidelines:

• Take the capsule with a full glass of water
• Can be taken with or without food
• Follow the prescribed duration strictly to ensure complete recovery

Side Effects

Avlosef Capsule is generally well tolerated. However, some side effects may include:

• Nausea, vomiting, diarrhea
• Abdominal pain or discomfort
• Skin rash or itching
• Hypersensitivity reactions (rare but serious)

Consult a healthcare professional if any severe or persistent side effects occur.

Precautions & Warnings

• Use with caution in patients with known allergy to cephalosporins or penicillins
• Dose adjustment may be required in patients with renal impairment
• Prolonged use may lead to superinfection
• Complete the full course to prevent antibiotic resistance

Drug Interactions

• Use cautiously with nephrotoxic drugs as it may increase the risk of kidney damage
• May interfere with certain diagnostic tests

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Use in Special Populations

• Pregnancy: Should be used only if clearly necessary
• Lactation: Excreted in small amounts in breast milk; generally considered safe
• Elderly: May require dose adjustment based on renal function

Storage

• Store below 25°C in a dry place
• Keep away from direct light and moisture
• Keep out of reach of children.