Benozol BR Suspension combines Brinzolamide 1% and Brimonidine Tartrate 0.2% in a single ophthalmic formulation, designed to reduce elevated intraocular pressure (IOP) in patients with glaucoma or ocular hypertension. This dual-action suspension works synergistically: Brinzolamide decreases aqueous humor production, while Brimonidine both reduces aqueous humor formation and increases uveoscleral outflow, providing enhanced IOP-lowering efficacy.

This combination therapy is ideal for patients who require more than one medication to achieve target IOP, offering convenience, improved compliance, and effective glaucoma management.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Significantly lowers elevated intraocular pressure
• Protects the optic nerve from pressure-related damage
• Dual mechanism enhances IOP reduction
• Convenient combination therapy reduces the need for multiple eye drops
• Suitable for long-term glaucoma and ocular hypertension management

Indications

Benozol BR Suspension is indicated for:

• Open-angle glaucoma
• Ocular hypertension
• Patients requiring dual therapy for optimal intraocular pressure control

Mechanism of Action

• Brinzolamide (1%): A carbonic anhydrase inhibitor that reduces aqueous humor production, lowering intraocular pressure.
• Brimonidine Tartrate (0.2%): An alpha-2 adrenergic agonist that decreases aqueous humor formation and increases uveoscleral outflow.
• The combination provides additive IOP-lowering effects while minimizing the need for multiple separate medications.

Dosage and Administration

• Instill 1 drop into the affected eye(s) 2–3 times daily or as prescribed by a physician
• Shake the bottle well before each use to ensure uniform suspension
• Wash hands before administration and avoid touching the dropper tip to the eye
• Remove contact lenses prior to administration; reinsert 15 minutes after use

Side Effects

Common side effects:

• Eye burning, stinging, or irritation
• Temporary blurred vision
• Bitter or unusual taste in the mouth

Rare side effects:

• Allergic reactions such as redness, itching, or swelling
• Eye dryness or corneal irritation
• Headache, dizziness, or fatigue in sensitive individuals

Precautions and Warnings

• For ophthalmic use only
• Avoid contamination of the dropper tip
• Use with caution in patients with cardiovascular disease, severe kidney or liver impairment
• Discontinue and consult a physician if severe eye irritation or hypersensitivity occurs

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Contraindications

• Hypersensitivity to Brinzolamide, Brimonidine, sulfonamides, or any component of the formulation
• Use in neonates or infants under 2 years without medical supervision
• Severe renal impairment without physician guidance

Storage Instructions

• Store below 30°C in a dry place
• Protect from light and contamination
• Keep out of reach of children.