Betacor HZ Tablet combines Bisoprolol Fumarate 5 mg, a selective beta-1 blocker, with Hydrochlorothiazide 6.25 mg, a thiazide diuretic, to provide effective management of hypertension. This dual-action formulation works synergistically: Bisoprolol reduces heart rate and cardiac workload, while Hydrochlorothiazide promotes the excretion of excess sodium and water, lowering blood volume and blood pressure.

By addressing hypertension through complementary mechanisms, Betacor HZ improves cardiovascular outcomes, reduces the risk of stroke and heart attack, and simplifies treatment by combining two agents in a single tablet.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Effectively lowers high blood pressure through dual mechanisms
• Reduces heart rate and myocardial oxygen demand
• Promotes fluid excretion to lower blood volume and vascular pressure
• Supports long-term cardiovascular health
• Convenient combination therapy enhances patient compliance

Indications

Betacor HZ Tablet is indicated for:

• Hypertension (high blood pressure)
• Patients requiring combination therapy for optimal blood pressure control
• Patients at risk of cardiovascular complications due to uncontrolled hypertension

Mechanism of Action

• Bisoprolol Fumarate (5 mg): Selectively blocks beta-1 adrenergic receptors in the heart, reducing heart rate, cardiac output, and myocardial oxygen demand.
• Hydrochlorothiazide (6.25 mg): Inhibits sodium reabsorption in the distal convoluted tubules of the kidneys, increasing sodium and water excretion, reducing blood volume, and lowering blood pressure.
• The combination provides complementary blood pressure-lowering effects, targeting both cardiac output and vascular volume.

Dosage and Administration

• Usually administered once daily or as prescribed by a physician
• Swallow the tablet whole with water, with or without food
• Do not discontinue therapy abruptly; sudden cessation may worsen hypertension or angina
• Dose adjustments should be guided by a healthcare professional based on blood pressure and heart rate response

Side Effects

Common side effects:

• Fatigue or mild tiredness
• Dizziness or lightheadedness
• Slow heart rate (bradycardia)
• Increased urination due to diuretic effect

Rare side effects:

• Electrolyte imbalance (low potassium or sodium)
• Swelling of extremities
• Shortness of breath or wheezing in sensitive patients

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Monitor blood pressure, heart rate, and electrolytes regularly
• Use with caution in patients with kidney or liver disease, diabetes, or severe cardiac conditions
• Inform your physician of all medications being taken to avoid interactions
• Avoid abrupt discontinuation of therapy

Contraindications

• Severe bradycardia or heart block greater than first degree without pacemaker
• Cardiogenic shock or decompensated heart failure
• Hypersensitivity to Bisoprolol, Hydrochlorothiazide, or any component of the tablet
• Severe renal or hepatic impairment without medical supervision

Storage Instructions

• Store below 30°C in a dry place
• Protect from light and moisture
• Keep in the original container
• Keep out of reach of children.