Nutridex Injection 25% is a sterile intravenous preparation containing Dextrose, a simple form of glucose that serves as a vital source of energy for the body. It is widely used in hospital and clinical settings to manage conditions associated with hypoglycemia (low blood sugar), fluid and electrolyte imbalance, and increased energy requirements. Due to its rapid availability as an energy substrate, Nutridex Injection 25% plays an important role in emergency care and supportive therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Dextrose

• Strength: 25% w/v

• Dosage Form: Intravenous injection

Therapeutic Class

• Carbohydrate solution / Parenteral nutrition and energy supplement

Indications

Nutridex Injection 25% is indicated for the treatment and management of several clinical conditions, including:

• Acute and severe hypoglycemia

• Insulin-induced hypoglycemia in diabetic patients

• Energy supplementation when oral intake is not possible

• Part of parenteral nutrition regimens

• Fluid and calorie replacement therapy

• Shock, trauma, or post-operative states requiring rapid energy supply

• Prevention and treatment of carbohydrate depletion

It is commonly used in critically ill patients where immediate correction of blood glucose levels is essential.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Mechanism of Action

Dextrose is a readily metabolizable form of glucose. After intravenous administration, it rapidly enters the bloodstream and is taken up by body cells. It is then utilized in cellular metabolism to produce energy in the form of ATP. This quick energy release helps restore normal blood glucose levels, supports vital organ function, and prevents complications associated with glucose deficiency, such as confusion, seizures, or loss of consciousness.

In addition, dextrose helps spare body proteins from being broken down for energy and supports overall metabolic balance.

Dosage and Administration

Nutridex Injection 25% is intended for intravenous use only and should be administered under strict medical supervision. The dose and rate of infusion depend on the patient’s age, body weight, clinical condition, and blood glucose levels.

• In adults, it is often given as a slow intravenous injection or infusion

• In pediatric or neonatal patients, dosing must be carefully adjusted to avoid hyperglycemia

Frequent monitoring of blood glucose levels is recommended during administration to ensure safe and effective therapy.

Side Effects

When used appropriately, Nutridex Injection 25% is generally well tolerated. However, possible side effects may include:

• Hyperglycemia (high blood sugar)

• Local irritation or pain at the injection site

• Thrombophlebitis with prolonged IV use

• Fluid overload, especially in patients with cardiac or renal impairment

• Electrolyte imbalance with excessive or prolonged use

Rapid infusion may increase the risk of adverse effects, so controlled administration is essential.

Precautions and Warnings

• Use with caution in patients with diabetes mellitus

• Careful monitoring is required in patients with heart failure, renal impairment, or dehydration

• Not recommended for use in patients with hyperglycemia or glucose intolerance unless clearly indicated

• Blood glucose and electrolyte levels should be monitored regularly

• Should not be mixed with incompatible medications without proper compatibility checks

Use in Pregnancy and Lactation

Nutridex Injection 25% may be used during pregnancy and breastfeeding if clearly needed and prescribed by a physician, as glucose is a natural body nutrient.

Storage

Store Nutridex Injection 25% below 30°C, protected from light. Do not freeze. Keep out of reach of children. Use only if the solution is clear and the container is intact.