Bupi Injection 0.50% contains Bupivacaine Hydrochloride, a long-acting local anesthetic used for regional, epidural, and peripheral nerve blocks. It provides effective anesthesia and analgesia during surgical, obstetric, and diagnostic procedures, allowing pain-free interventions.

Bupivacaine works by blocking sodium ion influx in nerve cells, which inhibits nerve impulse transmission and prevents pain signals from reaching the brain. Its long duration of action makes it suitable for procedures that require extended anesthesia or postoperative pain control.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Provides long-lasting local anesthesia and analgesia
• Suitable for surgical, obstetric, and diagnostic procedures
• Rapid onset of pain relief for targeted regions
• Can be used in epidural, spinal, or peripheral nerve blocks
• Reduces the need for systemic analgesics postoperatively

Indications

Bupi Injection 0.50% is indicated for:

• Surgical anesthesia for minor or major procedures
• Epidural anesthesia during labor and delivery
• Regional and peripheral nerve blocks for pain management
• Postoperative pain control in specific surgical interventions

Mechanism of Action

Bupivacaine Hydrochloride is an amide-type local anesthetic. It works by:

• Inhibiting sodium ion channels in neuronal membranes
• Blocking nerve impulse propagation in sensory and motor nerves
• Providing both anesthesia (loss of sensation) and analgesia (pain relief) for a prolonged duration

Dosage and Administration

• Administered by a trained healthcare professional only
• Dosage depends on the type, location, and duration of the procedure, as well as patient condition
• Use aseptic technique to prevent infection
• Monitor cardiovascular and respiratory function during administration
• Adjust dose for elderly patients, infants, or patients with hepatic or cardiac impairment

Side Effects

Common side effects:

• Mild burning or discomfort at the injection site
• Temporary numbness or weakness in the injected region

Rare but serious side effects:

• Hypotension, bradycardia, or arrhythmias
• Allergic reactions including rash, swelling, or anaphylaxis
• CNS toxicity: dizziness, seizures, or confusion in rare cases

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use with caution in patients with cardiovascular, hepatic, or renal impairment
• Avoid intravascular injection to prevent systemic toxicity
• Monitor vital signs and have resuscitation equipment available
• Not recommended for patients with known hypersensitivity to amide-type anesthetics

Contraindications

• Hypersensitivity to Bupivacaine or other amide local anesthetics
• Severe heart block or unstable cardiovascular conditions without appropriate monitoring
• Intravascular injection or use in untrained settings

Storage Instructions

• Store below 30°C in a dry place
• Protect from light and freezing
• Keep out of reach of children.