Caloren Injection contains Calcitriol 1 mcg/ml, the active form of vitamin D3, used for the management of hypocalcemia, renal osteodystrophy, and other disorders related to calcium and phosphate imbalance. Calcitriol plays a crucial role in regulating calcium and phosphorus metabolism in the body, supporting healthy bones, teeth, and muscular function.

This injectable formulation ensures rapid and precise delivery of Calcitriol directly into the bloodstream, making it ideal for patients who cannot tolerate oral supplementation or require immediate correction of calcium deficiency.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Caloren Injection is indicated for:

• Treatment of hypocalcemia in patients with chronic kidney disease or after parathyroid surgery
• Management of renal osteodystrophy in patients undergoing dialysis
• Prevention and treatment of secondary hyperparathyroidism associated with chronic renal failure
• Support in bone mineralization disorders due to vitamin D deficiency

Composition

• Active Ingredient: Calcitriol
• Strength: 1 mcg per ml
• Dosage Form: Injectable solution

Mechanism of Action

Calcitriol is the biologically active form of vitamin D3. It:

• Increases intestinal absorption of calcium and phosphate
• Enhances bone mineralization
• Suppresses excessive parathyroid hormone (PTH) secretion
• Maintains serum calcium and phosphate balance, reducing risk of bone disease and muscular weakness

By correcting calcium and phosphate levels, Calcitriol supports skeletal health and prevents complications associated with chronic kidney disease or metabolic bone disorders.

Dosage & Administration

• Administered intravenously or subcutaneously under medical supervision
• Adults: 0.25–0.5 mcg once daily or as directed by a physician; dose may be adjusted based on serum calcium levels
• Pediatrics: Dose individualized according to body weight and clinical condition
• Monitor serum calcium and phosphate levels regularly during therapy
• Avoid rapid or excessive dosing to prevent hypercalcemia

Side Effects

Caloren Injection is generally well tolerated when used under medical supervision. Possible side effects include:

• Hypercalcemia (high blood calcium)
• Nausea or vomiting
• Weakness or fatigue
• Headache
• Rare: arrhythmias, kidney stones, or excessive thirst

Seek medical attention immediately if symptoms of hypercalcemia occur, such as confusion, muscle pain, or irregular heartbeat.

Precautions & Warnings

• Monitor serum calcium and phosphate regularly to prevent overdose
• Use cautiously in patients with kidney disease, heart disease, or hypercalcemia
• Avoid simultaneous use of other vitamin D supplements unless advised by a physician
• Do not use for prophylactic purposes without medical supervision

Drug Interactions

• May interact with digoxin, thiazide diuretics, or other vitamin D analogs
• Inform your healthcare provider about all medications being taken

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Use in Special Populations

• Pregnancy: Use only if clearly necessary under medical supervision
• Lactation: Consult a physician before use
• Elderly: Monitor for hypercalcemia and renal function
• Pediatrics: Use cautiously under specialist guidance

Storage

• Store below 25°C in a cool, dry place
• Protect from light and moisture
• Keep ampoules tightly closed
• Keep out of reach of children.