Candicon Tablet 200 mg contains Voriconazole, a broad-spectrum triazole antifungal agent used to treat serious fungal infections. It is highly effective against invasive infections caused by Aspergillus, Candida, Fusarium, and other susceptible fungal species. This higher-strength tablet is suitable for patients requiring intensive therapy or higher dosing for severe infections.

Voriconazole works by inhibiting the fungal cytochrome P450 enzyme 14α-sterol demethylase, disrupting ergosterol synthesis—a critical component of the fungal cell membrane. This interference compromises membrane integrity, resulting in fungal cell death.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Treats serious and invasive fungal infections effectively
• Broad-spectrum activity against Aspergillus, Candida, and other resistant fungi
• Suitable for high-dose therapy in severe infections
• Rapid absorption and high bioavailability
• Supports management of infections in immunocompromised patients

Indications

Candicon Tablet 200 mg is indicated for:

• Invasive aspergillosis
• Candidemia and invasive candidiasis
• Serious fungal infections in immunocompromised patients
• Fusarium and Scedosporium infections
• Prophylaxis of fungal infections in high-risk patients

Mechanism of Action

Voriconazole is a triazole antifungal that:

• Inhibits fungal 14α-sterol demethylase
• Prevents ergosterol synthesis, disrupting fungal cell membranes
• Leads to inhibition of fungal growth and cell death

Dosage and Administration

• Take as prescribed by a physician, usually 200 mg twice daily for adults
• Swallow the tablet whole with water, preferably on an empty stomach for optimal absorption
• Dosage adjustments may be required in patients with liver impairment
• Regular monitoring of liver function and drug interactions is recommended

Side Effects

Common side effects:

• Nausea, vomiting, or diarrhea
• Headache or dizziness
• Visual disturbances such as blurred vision or altered color perception

Rare side effects:

• Liver enzyme elevation and hepatotoxicity
• Allergic reactions including rash, swelling, or itching
• Cardiac arrhythmias in susceptible patients

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use cautiously in patients with liver dysfunction
• Monitor for drug interactions, as Voriconazole is metabolized via CYP450 enzymes
• Not recommended during pregnancy or breastfeeding unless directed by a physician
• Liver function tests are advised during prolonged therapy

Contraindications

• Hypersensitivity to Voriconazole or other azole antifungals
• Severe liver impairment without medical supervision
• Concomitant use of drugs strongly contraindicated with Voriconazole

Storage Instructions

• Store below 30°C in a dry, dark place
• Keep the tablet in its original packaging to protect from moisture
• Keep out of reach of children.