Co-Valtin Tablet 5 mg + 160 mg is a fixed-dose combination antihypertensive medicine containing Amlodipine Besilate, a calcium channel blocker, and Valsartan, an angiotensin II receptor blocker (ARB). This dual-action formulation is intended for patients with hypertension who require stronger or more comprehensive blood pressure control than can be achieved with single-agent therapy. By targeting two different physiological pathways, Co-Valtin Tablet helps achieve sustained blood pressure reduction and lowers the risk of cardiovascular complications.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Amlodipine Besilate: 5 mg

• Valsartan: 160 mg

• Dosage Form: Film-coated tablet

• Route of Administration: Oral

Mechanism of Action

Amlodipine works by inhibiting calcium ion influx into vascular smooth muscle cells, resulting in relaxation and widening of blood vessels. This reduces peripheral vascular resistance and improves blood flow.
Valsartan selectively blocks the binding of angiotensin II to its receptors, preventing vasoconstriction and reducing aldosterone secretion. This leads to decreased sodium and water retention and further vasodilation. The combination provides additive antihypertensive effects with improved tolerability.

Indications

Co-Valtin Tablet 5 mg + 160 mg is indicated for:

• Treatment of essential hypertension

• Patients whose blood pressure is not adequately controlled with monotherapy

• Long-term management of hypertension to reduce the risk of stroke, myocardial infarction, and other cardiovascular events

Dosage and Administration

• The usual recommended dose is one tablet once daily, or as directed by a physician.

• The tablet should be swallowed whole with water and can be taken with or without food.

• Dose adjustments may be made based on blood pressure response and patient tolerance.

Regular use at the same time each day is advised for optimal blood pressure control.

Contraindications

Co-Valtin Tablet is contraindicated in:

• Patients with known hypersensitivity to amlodipine, valsartan, or any excipient

• Severe hepatic impairment or cholestasis

• Pregnancy, particularly during the second and third trimesters

Precautions and Warnings

• Use with caution in patients with renal impairment, heart failure, or volume depletion

• Blood pressure, renal function, and serum electrolytes should be monitored periodically

• Dizziness or lightheadedness may occur, especially during the initial phase of treatment

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Commonly reported side effects include:

• Dizziness or headache

• Peripheral edema

• Fatigue

Less common effects may include hypotension, nausea, or abdominal discomfort.

Storage

Store below 30°C in a cool and dry place. Protect from light and moisture. Keep out of reach of children.

Conclusion

Co-Valtin Tablet 5 mg + 160 mg provides a powerful and convenient combination therapy for effective hypertension management. Its dual mechanism of action supports sustained blood pressure control and helps reduce long-term cardiovascular risk when used under medical supervision.