Colasa Tablet 400 mg contains Mesalazine (5-Aminosalicylic Acid) 400 mg, an anti-inflammatory medicine widely used in the treatment and maintenance of inflammatory bowel diseases (IBD), particularly ulcerative colitis. It works directly on the lining of the intestine to reduce inflammation, relieve symptoms, and promote healing of the intestinal mucosa.

Ulcerative colitis is a chronic inflammatory condition affecting the colon and rectum, characterized by symptoms such as abdominal pain, diarrhea, rectal bleeding, and urgency. Mesalazine belongs to the aminosalicylate class of medications and is considered a first-line therapy for mild to moderate ulcerative colitis. It acts locally in the colon, minimizing inflammation and preventing flare-ups.

Colasa Tablet 400 mg is designed to release mesalazine in the intestine, where it exerts its therapeutic action. By reducing inflammatory processes in the bowel, it helps control active disease and maintain long-term remission.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Colasa Tablet 400 mg is indicated for:

• Mild to moderate ulcerative colitis

• Maintenance of remission in ulcerative colitis

• Inflammatory bowel disease involving the colon

• Prevention of relapse in chronic ulcerative colitis

Key Benefits

• Reduces inflammation in the colon

• Controls symptoms such as diarrhea, bleeding, and abdominal discomfort

• Promotes healing of the intestinal lining

• Helps maintain long-term remission

• Suitable for both acute treatment and maintenance therapy

Mechanism of Action

Mesalazine works by inhibiting the production of inflammatory mediators such as prostaglandins and leukotrienes in the intestinal mucosa. It blocks cyclooxygenase and lipoxygenase pathways, thereby decreasing inflammation and oxidative stress in the colon. This targeted anti-inflammatory effect helps improve symptoms and supports mucosal healing.

Dosage and Administration

The dosage of Colasa Tablet 400 mg should be determined by a healthcare professional based on the severity of the disease and patient response. It is typically taken in divided doses throughout the day, with or without food.

Tablets should be swallowed whole with water and should not be crushed or chewed unless advised by a physician. Consistent use as prescribed is essential to achieve optimal results and prevent relapse.

Precautions

• Use cautiously in patients with kidney or liver impairment.

• Regular monitoring of renal function is recommended during prolonged therapy.

• Inform your physician if you have a history of allergy to salicylates or aspirin.

• Not recommended for patients with severe renal disease unless directed by a healthcare provider.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Colasa Tablet is generally well tolerated. However, some individuals may experience:

• Nausea or vomiting

• Abdominal pain

• Headache

• Diarrhea

• Skin rash (rare)

Serious adverse effects are uncommon but require immediate medical attention if they occur.

Storage

Store below 30°C in a cool, dry place, protected from moisture and direct sunlight. Keep out of reach of children.